Survival of Breast Cancer by Stage, Grade and Molecular Groups in Mallorca, Spain

The aims of this study are: (1) to determine cause-specific survival by stage, grade, and molecular groups of breast cancer, (2) to identify factors which explain and predict the likelihood of survival and the risk of dying from this cancer; and (3) to find out the distribution of breast cancer case...

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Bibliographic Details
Published in:Journal of clinical medicine 2022-09, Vol.11 (19), p.5708
Main Authors: Pascual, Maria Clara, Montaño, Juan José, Franch, Paula, Sánchez-Contador, Carmen, Ramos, Maria
Format: Article
Language:English
Subjects:
Age
Breast cancer
Classification
Clinical medicine
Estrogens
Histology
Medical prognosis
Methods
Mortality
Survival analysis
Variables
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Summary:The aims of this study are: (1) to determine cause-specific survival by stage, grade, and molecular groups of breast cancer, (2) to identify factors which explain and predict the likelihood of survival and the risk of dying from this cancer; and (3) to find out the distribution of breast cancer cases by stage, grade, and molecular groups in females diagnosed in the period 2006–2012 in Mallorca (Spain). We collected data regarding age, date and diagnostic method, histology, laterality, sublocation, pathological or clinical tumor size (T), pathological or clinical regional lymph nodes (N), metastasis (M) and stage, histologic grade, estrogen and progesterone receptors status, HER-2 expression, Ki67 level, molecular classification, date of last follow-up or date of death, and cause of death. We identified 2869 cases. Cause-specific survival for the entire sample was 96% 1 year after diagnosis, 91% at 3 years and 87% at 5 years. Relative survival was 96.9% 1 year after diagnosis, 92.6% at 3 years and 88.5% at 5 years. The competing-risks regression model determined that patients over 65 years of age and patients with triple negative cancer have worse prognoses, and as stages progress, the prognosis for breast cancer worsens, especially from stage III.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm11195708