Temperature-Responsive Polymer Brush Coatings for Advanced Biomedical Applications

Modern biomedical technologies predict the application of materials and devices that not only can comply effectively with specific requirements, but also enable remote control of their functions. One of the most prospective materials for these advanced biomedical applications are materials based on...

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Bibliographic Details
Published in:Polymers 2022-10, Vol.14 (19), p.4245
Main Authors: Nastyshyn, Svyatoslav, Stetsyshyn, Yuriy, Raczkowska, Joanna, Nastishin, Yuriy, Melnyk, Yuriy, Panchenko, Yuriy, Budkowski, Andrzej
Format: Article
Language:English
Subjects:
Adsorption
Bacteria
Biocompatibility
Biomedical engineering
Biomedical materials
Coatings
Efficiency
Physiology
Polymer industry
Polymers
Protein adsorption
Proteins
Remote control
Review
Technology application
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Summary:Modern biomedical technologies predict the application of materials and devices that not only can comply effectively with specific requirements, but also enable remote control of their functions. One of the most prospective materials for these advanced biomedical applications are materials based on temperature-responsive polymer brush coatings (TRPBCs). In this review, methods for the fabrication and characterization of TRPBCs are summarized, and possibilities for their application, as well as the advantages and disadvantages of the TRPBCs, are presented in detail. Special attention is paid to the mechanisms of thermo-responsibility of the TRPBCs. Applications of TRPBCs for temperature-switchable bacteria killing, temperature-controlled protein adsorption, cell culture, and temperature-controlled adhesion/detachment of cells and tissues are considered. The specific criteria required for the desired biomedical applications of TRPBCs are presented and discussed.
ISSN:2073-4360
2073-4360
DOI:10.3390/polym14194245