Time to antibiotics (TTA) in paediatric patients with fever in the setting of neutropenia

Introduction Immunocompromised cancer patients are at elevated risk of infections.1 The major contributing factors that predispose cancer patients to immunodeficiency include the underlying disease and related management.2 Febrile neutropenia is a common and life-threatening complication in paediatr...

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Bibliographic Details
Published in:Clinical medicine (London, England) England), 2022-07, Vol.22 (4), p.82-83
Main Authors: Butt, Anosha Jabeen, Kanwal, Fareeha, Hafeez, Haroon, Nasir, Khawaja Shehryar, Abrar, Wajeeha, Munawar, Marrium, Yaqub, Samran
Format: Article
Language:English
Subjects:
Antibiotics
Cancer therapies
Chemotherapy
Emergency medical care
Fever
Infections
Intervention
Morbidity
Mortality
Neutropenia
Pediatrics
Process controls
Quality improvement
Quality Improvement and Patient Safety
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Summary:Introduction Immunocompromised cancer patients are at elevated risk of infections.1 The major contributing factors that predispose cancer patients to immunodeficiency include the underlying disease and related management.2 Febrile neutropenia is a common and life-threatening complication in paediatric cancer patients on chemotherapy.3,4 It is characterised by fever (temperature ≥38.3°C (101°F) or ≥38°C (100.4°F) for at least 1 hour).2 Bacterial infection facilitated by immunosuppression is the vital cause of mortality and morbidity in cancer patients.5 Morbidity and mortality correlated with this situation can be minimised if the clinicians initiate antibiotic treatment expeditiously.3 It has been established that the administration of antibiotics in patients presenting with febrile neutropenia in
ISSN:1470-2118
1473-4893
DOI:10.7861/clinmed.22-4-s82