Does Abdominal Obesity Increase All-Cause, Cardiovascular Disease, and Cancer Mortality Risks in Older Adults? A 10-Year Follow-Up Analysis

There is insufficient evidence on the impact of abdominal obesity (AO) on mortality in older adults. Therefore, the objective to analyze the 10-year impact of AO, assessed using different diagnostic criteria, on all-cause, cardiovascular disease (CVD), and cancer mortality in older adults. In this p...

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Bibliographic Details
Published in:Nutrients 2022-10, Vol.14 (20), p.4315
Main Authors: Moura, Letícia de Almeida Nogueira e, Pagotto, Valéria, Camargo Pereira, Cristina, de Oliveira, Cesar, Silveira, Erika Aparecida
Format: Article
Language:English
Subjects:
Abdomen
Adults
Aged
Body composition
Brazil
Cancer
Cardiovascular disease
Cardiovascular diseases
Chronic illnesses
Complications and side effects
Diabetes
Diagnostic systems
Health aspects
Health risks
Hypertension
Impact analysis
Laboratory tests
Lifestyles
Mortality
Obesity
Older people
Oncology, Experimental
Patient outcomes
Population
Prognosis
Public health
Risk analysis
Risk factors
Sociodemographics
Womens health
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Summary:There is insufficient evidence on the impact of abdominal obesity (AO) on mortality in older adults. Therefore, the objective to analyze the 10-year impact of AO, assessed using different diagnostic criteria, on all-cause, cardiovascular disease (CVD), and cancer mortality in older adults. In this prospective cohort study of older adults (≥60 years), sociodemographic, lifestyle, clinical history, laboratory test, and anthropometric data were analyzed. The considered were used for AO diagnostic: waist circumference (WC) of ≥88 cm for women and ≥102 cm for men; WC of ≥77.8 cm for women and ≥98.8 cm for men; and increased waist-to-hip ratio (WHR), being the highest tertile of distribution by sex. Multivariate Cox regression and Kaplan–Meier analyses were performed. A total of 418 individuals, with an average age of 70.69 ± 7.13 years, participated in the study. In the analysis adjusted for sex and age, WHR was associated with a high risk of all-cause mortality (p = 0.044). Both cutoff points used for the WC were associated with an increased CVD mortality risk. None of the AO parameters were associated with cancer mortality. An increased WHR was associated to a higher all-cause mortality risk factor, while an increased WC was a risk factor for a higher CVD mortality in older adults.
ISSN:2072-6643
2072-6643
DOI:10.3390/nu14204315