Life Instability Associated with Lower ART Adherence and Other Poor HIV-Related Care Outcomes in Older Adults with HIV

Background Life instability may be an important factor for HIV-related care outcomes in older adults living with HIV (OALWH). This study examined the degree to which an 11-item life instability index (LII) composed of individual- and community-level indicators was associated with HIV-related care ou...

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Bibliographic Details
Published in:International journal of behavioral medicine 2023-06, Vol.30 (3), p.345-355
Main Authors: Weinstein, Elliott R., Harkness, Audrey, Ironson, Gail, Shrader, Cho-Hee, Duncan, Dustin T., Safren, Steven A.
Format: Article
Language:English
Subjects:
Aged
Anti-Retroviral Agents - therapeutic use
Antiretroviral drugs
Antiretroviral therapy
Anxiety
Anxiety - epidemiology
Drug use
Family Medicine
Full Length Manuscript
General Practice
Health Psychology
HIV
HIV Infections - complications
HIV Infections - drug therapy
HIV Infections - epidemiology
Human immunodeficiency virus
Humans
Instability
Medication Adherence
Medicine
Medicine & Public Health
Mental depression
Older people
Patient compliance
Self Report
Substance use
Substance-Related Disorders - epidemiology
Viral Load
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Summary:Background Life instability may be an important factor for HIV-related care outcomes in older adults living with HIV (OALWH). This study examined the degree to which an 11-item life instability index (LII) composed of individual- and community-level indicators was associated with HIV-related care outcomes—viral load, antiretroviral (ART) medication adherence, rates of detectable viral load, and HIV care appointment non-adherence among OALWH in the Miami area. Methods Six hundred twenty-three OALWH completed an interviewer-administered assessment (English or Spanish), which was matched with medical record data. Results Participants reported about six LII indicators each (M = 6.08, SD = 1.44). Greater index scores were associated with worse self-reported ART adherence ( b  =  − 1.14, p  = 0.03), lower observed appointment adherence ( b  = 0.02, p  
ISSN:1070-5503
1532-7558
DOI:10.1007/s12529-022-10095-5