Collecting duct renal cell carcinoma: a single centre series and review of the literature

All cases had clear Bellini duct renal cell carcinoma appearance on microscopy with infiltrative tubular architecture and high-grade nuclear features. The latter explains the use of chemotherapeutic regimens, after surgical resection if feasible, rather than tyrosine kinase inhibitor (TKI) or immuno...

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Bibliographic Details
Published in:Central European journal of urology 2022-01, Vol.75 (3), p.252-256
Main Authors: Vanderbruggen, Wies, Claessens, Marc, De Coninck, Vincent, Duchateau, Aline, Gevaert, Thomas, Joniau, Steven, Hente, Robert
Format: Article
Language:English
Subjects:
Biopsy
Chemotherapy
Hematuria
Histology
Immunotherapy
Kidney cancer
Medical prognosis
Metastasis
Microscopy
NMR
Nuclear magnetic resonance
Oncology
Original Paper
Pathology
Surgery
Tumors
Urology
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Summary:All cases had clear Bellini duct renal cell carcinoma appearance on microscopy with infiltrative tubular architecture and high-grade nuclear features. The latter explains the use of chemotherapeutic regimens, after surgical resection if feasible, rather than tyrosine kinase inhibitor (TKI) or immunotherapy (IO) as a systemic treatment in most series [6]. All cases had clear Bellini duct renal cell carcinoma appearance on microscopy with infiltrative tubular architecture and high-grade nuclear features. There is no literature clarifying the place of cytoreductive nephrectomy in treatment of advanced CDRCC. Because of limited response to current systemic treatment, at present cytoreductive nephrectomy in conjunction to systematic treatment is suggested when feasible or for local symptom control [14]. All patients in our series had systemic treatment by means of combination chemotherapy: gem-citabine with platinum-based chemotherapy.
ISSN:2080-4873
2080-4806
2080-4873
DOI:10.5173/ceju.2022.0143