Comparison of clinical outcomes of pulmonary sequestration in adults between surgery and non-surgery groups

• Published in: Journal of thoracic disease 2022-10, Vol.14 (10), p.3876-3885
• Main Authors: Song, Ju Yeun, Park, Sung Goo, Lee, Ho Yun, Kim, Sae Rom, Kim, Han Gyeol, Shin, Sun Hye, Jeong, Byeong-Ho, Lee, Kyungjong, Kim, Hojoong, Kwon, O Jung, Han, Joungho, Kim, Jhingook, Um, Sang-Won
• Format: Article
• Language: English
• Subjects: Original
• ISSN: 2072-1439; 2077-6624
• DOI: 10.21037/jtd-22-631

BackgroundPulmonary sequestration (PS) is a rare congenital lung malformation that can be incidentally diagnosed in adulthood. The natural course of PS in adults is scarcely known. MethodsIn this retrospective cohort study, medical records and imaging results of adult patients diagnosed with PS between 1994 and 2019 were reviewed. Diagnoses of PS were confirmed by histopathological findings in resected cases, while non-resected cases were diagnosed based on the presence of anomalous systemic arterial supply and abnormal lung parenchyma on enhanced chest computed tomography (CT). ResultsAmong 104 patients with PS, the median age at diagnosis was 40.5 years, and 69 (66.3%) patients were asymptomatic. Patients in the surgery group were significantly younger (38.6 vs. 45.3 years, respectively, P=0.016), were more likely to be symptomatic initially (51.6% vs. 28.6%, respectively, P=0.015), and had larger PS (90.0 vs. 66.3 mm, respectively, P