Klebsiella invasive syndrome: a challenging diagnosis

Klebsiella invasive syndrome is a rare condition that typically presents as a liver abscess with metastatic infection, with mortality rates as high as 14% potentially due to diagnostic delay by clinicians. Here, we present a case of a woman in her 60s, who presented with symptoms and signs consisten...

Full description

Saved in:
Bibliographic Details
Published in:BMJ case reports 2022-11, Vol.15 (11), p.e251977
Main Authors: Bhide, Poorva Prashant, Ketkar, Apurva Avadhut, Almeligy, Abdalrahman, Ricca, Anthony
Format: Article
Language:English
Subjects:
Antibiotics
Bacterial infections
Case reports
Case Reports: Rare disease
Delayed Diagnosis
Female
Gram-negative bacteria
Humans
Klebsiella
Klebsiella Infections - diagnosis
Klebsiella Infections - drug therapy
Klebsiella pneumoniae
Liver Abscess - diagnostic imaging
Liver Abscess - pathology
Medical diagnosis
Syndrome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Klebsiella invasive syndrome is a rare condition that typically presents as a liver abscess with metastatic infection, with mortality rates as high as 14% potentially due to diagnostic delay by clinicians. Here, we present a case of a woman in her 60s, who presented with symptoms and signs consistent with meningitis, imaging findings suggestive of possible leptomeningeal carcinomatosis a long with areas of lung consolidation and abdominal nodules and lymphadenopathy, presumably metastatic malignancy. We diagnosed Klebsiella invasive syndrome and treated it conservatively with medical management, including a long course of intravenous antibiotic therapy and supportive care. This is an infrequently encountered clinical entity with potentially fatal consequences, and we hope to add to the existing literature on the subject and drive home the point that it should be considered in the differential diagnoses in the appropriate clinical scenario.
ISSN:1757-790X
1757-790X
DOI:10.1136/bcr-2022-251977