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Betulin, betulonic acid, 3-aminobetulinic acid. Improved extraction and preparative syntheses of derivatives

We optimized the process of extraction and purification of betulin from birch bark and modified preparative syntheses of the simplest derivatives of betulin, namely, betulonic acid, betulonic aldehyde, and 3-aminobetulinic acid, as a platform for subsequent modifications.

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Bibliographic Details
Published in:Russian chemical bulletin 2022, Vol.71 (10), p.2236-2240
Main Authors: Kaverin, M. V., Morozova, P. A., Snegur, L. V.
Format: Article
Language:English
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Summary:We optimized the process of extraction and purification of betulin from birch bark and modified preparative syntheses of the simplest derivatives of betulin, namely, betulonic acid, betulonic aldehyde, and 3-aminobetulinic acid, as a platform for subsequent modifications.
ISSN:1066-5285
1573-9171
DOI:10.1007/s11172-022-3651-7