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Examining Phenotypic Differences in Gaze Avoidance between Autism Spectrum Disorder and Fragile X Syndrome
We examined potential phenotypic differences in eye gaze avoidance exhibited by boys with autism spectrum disorder (ASD) and boys with fragile X syndrome (FXS). In Study 1, the Eye Contact Avoidance Scale (ECAS) was administered to caregivers of boys aged 7-18 years with FXS (n = 148), ASD (n = 168)...
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Published in: | American journal on intellectual and developmental disabilities 2022-11, Vol.127 (6), p.435-454 |
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container_title | American journal on intellectual and developmental disabilities |
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creator | Wilkinson, Ellen H Britton, Tobias C Hall, Scott S |
description | We examined potential phenotypic differences in eye gaze avoidance exhibited by boys with autism spectrum disorder (ASD) and boys with fragile X syndrome (FXS). In Study 1, the Eye Contact Avoidance Scale (ECAS) was administered to caregivers of boys aged 7-18 years with FXS (n = 148), ASD (n = 168), and mixed developmental disabilities (MDD; n = 128). In Study 2, subsets of boys with FXS (n = 31) and boys with ASD (n = 25) received a brief behavioral treatment probe to improve eye contact. Results showed that boys with FXS obtained significantly higher scores on the ECAS compared to boys with ASD and MDD. Exposure to the brief behavioral treatment probe resulted in significant decreases in scores for boys with FXS, but not for boys with ASD. |
doi_str_mv | 10.1352/1944-7558-127.6.435 |
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In Study 1, the Eye Contact Avoidance Scale (ECAS) was administered to caregivers of boys aged 7-18 years with FXS (n = 148), ASD (n = 168), and mixed developmental disabilities (MDD; n = 128). In Study 2, subsets of boys with FXS (n = 31) and boys with ASD (n = 25) received a brief behavioral treatment probe to improve eye contact. Results showed that boys with FXS obtained significantly higher scores on the ECAS compared to boys with ASD and MDD. Exposure to the brief behavioral treatment probe resulted in significant decreases in scores for boys with FXS, but not for boys with ASD.</description><identifier>ISSN: 1944-7515</identifier><identifier>EISSN: 1944-7558</identifier><identifier>DOI: 10.1352/1944-7558-127.6.435</identifier><identifier>PMID: 36306410</identifier><language>eng</language><publisher>United States: American Association on Intellectual and Developmental Disabilities</publisher><subject>Autism ; Autism Spectrum Disorder ; Autism Spectrum Disorders ; Autistic children ; Behavior ; Behavior Modification ; Behavior Patterns ; Behavior Therapy ; Boys ; Caregivers ; Child development ; Children & youth ; Communication ; Communication Skills ; Developmental Disabilities ; Environmental Influences ; Exhibits ; Eye contact ; Eye fixation ; Eye Movements ; Females ; Fixation, Ocular ; Fragile X Syndrome ; Genetic Disorders ; Girls ; Humans ; Hypotheses ; Intellectual disabilities ; Interpersonal Relationship ; Intervention ; Male ; Males ; Nonverbal Communication ; Program Effectiveness ; Psychiatry ; Psychological Patterns ; Social Behavior ; Social Development ; Social interaction ; Social Reinforcement ; Social skills ; Subsets ; Symptoms (Individual Disorders)</subject><ispartof>American journal on intellectual and developmental disabilities, 2022-11, Vol.127 (6), p.435-454</ispartof><rights>AAIDD.</rights><rights>Copyright American Association of Intellectual & Developmental Disabilities Nov 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c455t-bddd832b67de75f289b999b2ad197ca07ed497fe3d25982cef245adfc2212e423</citedby><cites>FETCH-LOGICAL-c455t-bddd832b67de75f289b999b2ad197ca07ed497fe3d25982cef245adfc2212e423</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.proquest.com/docview/2729568844/fulltextPDF?pq-origsite=primo$$EPDF$$P50$$Gproquest$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2729568844?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>230,314,777,781,882,12827,21359,21375,21376,27905,27906,30980,33592,33593,33858,33859,34511,34512,43714,43861,44096,73970,74146,74388</link.rule.ids><backlink>$$Uhttp://eric.ed.gov/ERICWebPortal/detail?accno=EJ1365357$$DView record in ERIC$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36306410$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wilkinson, Ellen H</creatorcontrib><creatorcontrib>Britton, Tobias C</creatorcontrib><creatorcontrib>Hall, Scott S</creatorcontrib><title>Examining Phenotypic Differences in Gaze Avoidance between Autism Spectrum Disorder and Fragile X Syndrome</title><title>American journal on intellectual and developmental disabilities</title><addtitle>Am J Intellect Dev Disabil</addtitle><description>We examined potential phenotypic differences in eye gaze avoidance exhibited by boys with autism spectrum disorder (ASD) and boys with fragile X syndrome (FXS). In Study 1, the Eye Contact Avoidance Scale (ECAS) was administered to caregivers of boys aged 7-18 years with FXS (n = 148), ASD (n = 168), and mixed developmental disabilities (MDD; n = 128). In Study 2, subsets of boys with FXS (n = 31) and boys with ASD (n = 25) received a brief behavioral treatment probe to improve eye contact. Results showed that boys with FXS obtained significantly higher scores on the ECAS compared to boys with ASD and MDD. Exposure to the brief behavioral treatment probe resulted in significant decreases in scores for boys with FXS, but not for boys with ASD.</description><subject>Autism</subject><subject>Autism Spectrum Disorder</subject><subject>Autism Spectrum Disorders</subject><subject>Autistic children</subject><subject>Behavior</subject><subject>Behavior Modification</subject><subject>Behavior Patterns</subject><subject>Behavior Therapy</subject><subject>Boys</subject><subject>Caregivers</subject><subject>Child development</subject><subject>Children & youth</subject><subject>Communication</subject><subject>Communication Skills</subject><subject>Developmental Disabilities</subject><subject>Environmental Influences</subject><subject>Exhibits</subject><subject>Eye contact</subject><subject>Eye fixation</subject><subject>Eye Movements</subject><subject>Females</subject><subject>Fixation, Ocular</subject><subject>Fragile X Syndrome</subject><subject>Genetic Disorders</subject><subject>Girls</subject><subject>Humans</subject><subject>Hypotheses</subject><subject>Intellectual disabilities</subject><subject>Interpersonal Relationship</subject><subject>Intervention</subject><subject>Male</subject><subject>Males</subject><subject>Nonverbal Communication</subject><subject>Program Effectiveness</subject><subject>Psychiatry</subject><subject>Psychological Patterns</subject><subject>Social Behavior</subject><subject>Social Development</subject><subject>Social interaction</subject><subject>Social Reinforcement</subject><subject>Social skills</subject><subject>Subsets</subject><subject>Symptoms (Individual 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subjects | Autism Autism Spectrum Disorder Autism Spectrum Disorders Autistic children Behavior Behavior Modification Behavior Patterns Behavior Therapy Boys Caregivers Child development Children & youth Communication Communication Skills Developmental Disabilities Environmental Influences Exhibits Eye contact Eye fixation Eye Movements Females Fixation, Ocular Fragile X Syndrome Genetic Disorders Girls Humans Hypotheses Intellectual disabilities Interpersonal Relationship Intervention Male Males Nonverbal Communication Program Effectiveness Psychiatry Psychological Patterns Social Behavior Social Development Social interaction Social Reinforcement Social skills Subsets Symptoms (Individual Disorders) |
title | Examining Phenotypic Differences in Gaze Avoidance between Autism Spectrum Disorder and Fragile X Syndrome |
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