Impact of Multiple Sclerosis and Its Association with Depression: An Analytical Case-Control Investigation

Multiple sclerosis (MS) is a neurological, chronic, inflammatory, and progressive disease with musculoskeletal problems and neurodegenerative disorders that causes worsening of the health status of patients. The aim of this study was to determine the level of depression in MS patients compared to a...

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Bibliographic Details
Published in:Healthcare (Basel) 2022-11, Vol.10 (11), p.2218
Main Authors: Ruiz-Sánchez, Francisco Javier, do Rosário Martins, Maria, Soares, Salete, Romero-Morales, Carlos, López-López, Daniel, Gómez-Salgado, Juan, Jiménez-Cebrián, Ana María
Format: Article
Language:English
Subjects:
Analysis
Ataxia
Biological markers
Biomarkers
Body mass index
Care and treatment
Complications and side effects
Cytokines
Depression, Mental
Diagnosis
Disease
Epidemiology
Ethics
Health aspects
Health care
Mental depression
Multiple sclerosis
Nervous system
Psychological aspects
Quality of life
Questionnaires
Software
Spasticity
Womens health
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Summary:Multiple sclerosis (MS) is a neurological, chronic, inflammatory, and progressive disease with musculoskeletal problems and neurodegenerative disorders that causes worsening of the health status of patients. The aim of this study was to determine the level of depression in MS patients compared to a population of healthy subjects. The established sample size was 116 subjects matched with the same age, sex, and body mass index. The subjects were recruited from different multiple sclerosis associations and neurology clinics in different public health areas (case group n = 58) and healthy subjects from the same locality (control group n = 58). The scores and categories of the Beck Depression Inventory (BDI) in its Spanish version were collected. There was a clear statistically significant difference (p < 0.05) in the BDI scores between both groups. As a result, we found that the subjects with MS presented worse results with BDI = 9.52 ± 7.70 points compared to the healthy subjects with a BDI score = 5.03 ± 5.14. Within the BDI categories, there were statistically significant differences (p < 0.001), which were greater for the MS group. Depression is a dangerous factor for MS patients, being a trigger for a poorer quality of life.
ISSN:2227-9032
2227-9032
DOI:10.3390/healthcare10112218