Efficacy and Safety of Topical Application of Olive Oil for Preventing Pressure Ulcers: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

The purpose was to identify and summarize the existing evidence on the efficacy and safety of the topical application of olive oil for preventing pressure ulcers (PUs). We included only randomized controlled trials (RCTs) involving patients at risk of developing PUs, testing the topical application...

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Bibliographic Details
Published in:International journal of environmental research and public health 2022-11, Vol.19 (22), p.14921
Main Authors: Hernández-Vásquez, Akram, Visconti-Lopez, Fabriccio J, Cabanillas-Ramirez, Cielo, Díaz-Seijas, Deysi, Meléndez-Escalante, Jessica, Comandé, Daniel, Santero, Marilina
Format: Article
Language:English
Subjects:
Bias
Citation management software
Clinical trials
Fatty acids
Humans
Incidence
Intervention
Meta-analysis
Olive Oil
Pressure Ulcer - epidemiology
Pressure Ulcer - prevention & control
Pressure ulcers
Prevention
Randomized Controlled Trials as Topic
Risk assessment
Skin
Suppuration
Systematic Review
Topical application
Ulcers
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Summary:The purpose was to identify and summarize the existing evidence on the efficacy and safety of the topical application of olive oil for preventing pressure ulcers (PUs). We included only randomized controlled trials (RCTs) involving patients at risk of developing PUs, testing the topical application of olive oil versus other products for PU prevention. We assessed the risk of bias using the RoB 2 tool, and the certainty of the evidence with GRADE. Four RCTs met the eligibility criteria. All studies were judged at a low risk of bias overall. The meta-analysis showed that the clinical efficacy of olive oil for prevention occurs by reducing the incidence of PUs (RR = 0.56, 95% CI = 0.30 to 0.79, = 0%); with no differences in adverse effects, it may be associated with a shorter development time of PUs and shorter hospital stays. The certainty of the evidence assessed by the GRADE approach was moderate and low. The topical application of olive oil is effective and safe in reducing the incidence of PUs compared to other treatments. These findings could provide new insights into olive oil as a preventive and alternative treatment for PUs as it is accessible and inexpensive compared to other products.
ISSN:1660-4601
1661-7827
1660-4601
DOI:10.3390/ijerph192214921