Bibliometric and Visualized Analysis of the Current Status on STING Signaling Pathway and Cancer

Cancer, as the second leading cause of death worldwide, has become an ongoing public health challenge and its treatment has received much attention, with immunotherapy becoming a hot research topic in recent years. The interferon gene stimulating factor (STING)-mediated signaling pathway has a “doub...

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Bibliographic Details
Published in:Journal of oncology 2022-11, Vol.2022, p.5095176-12
Main Authors: Lu, Zhongqi, Fu, Qiang, Sui, Jinyuan, Chang, Ying, Jin, Tiefeng, Zhang, Meihua
Format: Article
Language:English
Subjects:
Adapter proteins
Analysis
Bibliometrics
Biological response modifiers
Cancer
Cancer research
Collaboration
Endoplasmic reticulum
Exports
Immunotherapy
Interferon
Keywords
Metastasis
Mitochondrial DNA
Science
Software
Statistical analysis
Trends
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Summary:Cancer, as the second leading cause of death worldwide, has become an ongoing public health challenge and its treatment has received much attention, with immunotherapy becoming a hot research topic in recent years. The interferon gene stimulating factor (STING)-mediated signaling pathway has a “double-edged sword” role in cancer, which plays different roles in different types and stages of tumors. In this paper, we discuss the current research status, cooperation, and hotspots of STING signaling pathway in cancer from 2008–2022 using CiteSpace software based on the literature of cancer and STING signaling pathway. In addition, we predicted future research trends in this field by analysis, and the results showed that the STING signaling pathway is rapidly increasing in cancer research, and its role in tumor microenvironment and immunotherapy has become a new hot spot in current research and will continue to receive high attention.
ISSN:1687-8450
1687-8450
DOI:10.1155/2022/5095176