Factors influencing the participation of Black and White Americans in Alzheimer's disease biomarker research

Introduction Alzheimer's disease (AD) is a public health priority. AD biomarkers may vary based on race, but the recruitment of diverse participants has been challenging. Methods Three groups of Black and White participants with and without prior research advocacy or participation were intervie...

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Bibliographic Details
Published in:Alzheimer's & dementia : diagnosis, assessment & disease monitoring assessment & disease monitoring, 2022, Vol.14 (1), p.e12384-n/a
Main Authors: Eliacin, Johanne, Hathaway, Elizabeth, Wang, Sophia, O'Connor, Caitlin, Saykin, Andrew J., Cameron, Kenzie A.
Format: Article
Language:English
Subjects:
AD biomarker
Alzheimer's disease
Apolipoproteins
Biomarkers
Community
Data analysis
Data collection
Dementia
Focus groups
health disparity
Hispanic Americans
Interviews
Participation
Perceptions
Qualitative research
qualitative research methods
R&D
Race
racial diversity
Research & development
Research methodology
research participation
Veterans
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Summary:Introduction Alzheimer's disease (AD) is a public health priority. AD biomarkers may vary based on race, but the recruitment of diverse participants has been challenging. Methods Three groups of Black and White participants with and without prior research advocacy or participation were interviewed individually or in focus groups to better understand perspectives related to AD biomarker research participation. A rapid qualitative data analytic approach was used to analyze the data. Results Identified barriers to AD biomarker research participation included hesitancy due to fear, distrust of research and researchers, lack of relevant knowledge, and lack of research test results disclosure. Drivers for engagement in biomarker research procedures included knowledge about research, AD, and related clinical procedures, perceived benefits of participation, and outreach from trusted sources. Discussion Participants’ comments related to the need for diversity in research and desire for results disclosure suggest opportunities to engage Black individuals. Highlights Black Americans experience more salient barriers to Alzheimer's disease (AD) biomarker research participation. Concerns about research diversity influence research participation decisions. Research test disclosure may affect research participation and retention.
ISSN:2352-8729
2352-8729
DOI:10.1002/dad2.12384