Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone-A Pilot Case Study

This case study describes the use of additive manufacturing technology combining a biodegradable polymer material, polycaprolactone (PCL), and innovative procedures for creating superficial wound dressing, a scaffold in the therapy of extensive contaminated skin defects caused by a traumatic injury....

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Bibliographic Details
Published in:Polymers 2022-12, Vol.14 (23), p.5293
Main Authors: Findrik Balogová, Alena, Kožár, Martin, Staroňová, Radka, Schnitzer, Marek, Dancáková, Gabriela, Živčák, Jozef, Hudák, Radovan
Format: Article
Language:English
Subjects:
3-D printers
3D printing
Bacterial infections
Biocompatibility
Biodegradability
Care and treatment
Case studies
Comparative analysis
Contamination
Defects
Iodine
Mechanical properties
Methicillin
Microorganisms
Polycaprolactone
Polymers
Regeneration (physiology)
Scaffolds
Skin
Staphylococcus infections
Technology application
Therapy
Tissue engineering
Transplants
Transplants & implants
Wound healing
Wounds and injuries
Citations: Items that this one cites
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Summary:This case study describes the use of additive manufacturing technology combining a biodegradable polymer material, polycaprolactone (PCL), and innovative procedures for creating superficial wound dressing, a scaffold in the therapy of extensive contaminated skin defects caused by a traumatic injury. Chronic and contaminated wounds represent a clinical problem and require intensive wound care. The application of a temporary scaffold-facilitated bridging of the wound edges resulted in faster tissue regeneration and a shorter defect closure time, compared to other conservative and surgical methods used in therapy of chronic wounds. Although this procedure has proven to be an optimal alternative to autologous transplants, further studies with a larger number of patients would be beneficial.
ISSN:2073-4360
2073-4360
DOI:10.3390/polym14235293