Prognostic influence for hilar cholangiocarcinoma and comparisons of prognostic values of Mayo staging and TNM staging systems

• Published in: Medicine (Baltimore) 2022-12, Vol.101 (49), p.e32250-e32250
• Main Authors: Sun, Zhaowei, Sun, Xiaozhi, Guo, Jingyun, Li, Xueliang, Wang, Qinlei, Su, Na, Chen, Menshou, Cao, Guanghua, Yu, Yanan, Wang, Maobing, Li, Haoran, Zhong, Haochen, Zou, Hao, Ma, Kai, Shen, Fangzhen, Zhang, Bingyuan, Feng, Yujie
• Format: Article
• Language: English
• Subjects: Bile Duct Neoplasms - pathology; Humans; Kaplan-Meier Estimate; Klatskin Tumor - surgery; Neoplasm Staging; Observational Study; Prognosis; Retrospective Studies
• ISSN: 1536-5964; 0025-7974; 1536-5964
• DOI: 10.1097/MD.0000000000032250

The study was designed to discuss the effect of stratification factors in the Mayo staging on the prognosis of hilar cholangiocarcinoma (HCCA) patients, and to evaluate the predictive value of the Mayo staging on the prognosis. The Kaplan–Meier survival curve and Log-rank test were used to perform univariate analysis on each index and obtain statistically significant influencing factors. The Kaplan–Meier survival curve and Log-rank test were used to analyze the correlation between the two staging systems and the survival period. The receiver operating characteristic (ROC) curves were used for each single staging system trend analysis, and comparison of their curve area to determine prognosis prediction ability for patients with HCCA. According to Kaplan–Meier survival curve changes and Log-rank test results, it was found that both staging systems were correlated with the survival time of the patients ( P