Hospital frailty risk score predicts worse outcomes in patients with chronic pancreatitis

Chronic pancreatitis (CP) is a pathological fibroinflammatory response to persistent inflammation or stress to the pancreas. The effect of frailty on outcomes in patients with CP has not been previously examined. In this study, we examined the effect of frailty on outcomes in hospitalized patients w...

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Published in:Annals of gastroenterology 2023-01, Vol.36 (1), p.73-80
Main Authors: Sohal, Aalam, Chaudhry, Hunza, Kohli, Isha, Gupta, Gagan, Singla, Piyush, Sharma, Raghav, Dukovic, Dino, Prajapati, Devang
Format: Article
Language:English
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Summary:Chronic pancreatitis (CP) is a pathological fibroinflammatory response to persistent inflammation or stress to the pancreas. The effect of frailty on outcomes in patients with CP has not been previously examined. In this study, we examined the effect of frailty on outcomes in hospitalized patients with CP. Records of patients with a primary or secondary discharge diagnosis of CP (ICD10-CM codes K86.0, K86.1) between January 2016 and December 2019 were obtained from the National Inpatient Sample database. Data were collected on patient demographics, hospital characteristics, comorbidities, and etiology of CP. The relationship between frailty and outcomes, including mortality, intensive care unit (ICU) admission, sepsis, shock, length of stay (LOS), and total hospitalization charges (THC), were analyzed using multivariate analysis. 722,160 patients were included in the analysis. Patients with a high hospital frailty risk score had a higher mortality risk (adjusted odds ratio [aOR] 12.57, 95% confidence interval [CI] 10.42-15.16; P
ISSN:1108-7471
1792-7463
1792-7463
DOI:10.20524/aog.2022.0765