Characterization and genomic analysis of JC01, a novel bacteriophage infecting Cronobacter sakazakii

The lytic bacteriophage JC01 was isolated using a strain of Cronobacter sakazakii previously isolated from powdered infant formula (PIF). The complete genome sequence of phage JC01 was determined. The double-stranded DNA genome of phage JC01 is composed of 61,736 bp with a G + C content of 58.9%, an...

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Bibliographic Details
Published in:Archives of virology 2023-01, Vol.168 (1), p.1-1, Article 1
Main Authors: Jiang, Jie, Lan, Guanda, Li, Jinghua, Yu, Jun, Huang, Honglan, Sun, Yanbo, Xu, Cuiting, Liu, Dandan, Gong, Yunwei, Zhao, Chunyan
Format: Article
Language:English
Subjects:
Antibiotics
Baby foods
Bacteriophages
Biomedical and Life Sciences
Biomedicine
Brief Report
Cronobacter sakazakii
Cronobacter sakazakii - genetics
DNA
Drug resistance
Food contamination & poisoning
Genome, Viral
Genomes
Genomic analysis
Genomics
Humans
Infant
Infectious Diseases
Lysis
Medical Microbiology
Nucleotide sequence
Open Reading Frames
Phages
Phylogenetics
Phylogeny
Proteins
Salmonella
Transfer RNA
tRNA
Virology
Virulence
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Summary:The lytic bacteriophage JC01 was isolated using a strain of Cronobacter sakazakii previously isolated from powdered infant formula (PIF). The complete genome sequence of phage JC01 was determined. The double-stranded DNA genome of phage JC01 is composed of 61,736 bp with a G + C content of 58.9%, and it contains 76 putative open reading frames (ORFs) without any tRNA genes. The predicted ORFs were classified into functional groups, including DNA manipulation, transcription, phage packaging, phage structure, host lysis, and hypothetical proteins. Based on overall nucleotide sequence comparisons, calculation of phage intergenomic similarities, and phylogenetic analysis, JC01 appears to be a novel bacteriophage infecting C. sakazakii .
ISSN:0304-8608
1432-8798
DOI:10.1007/s00705-022-05663-9