Special Techniques of Adjuvant Breast Carcinoma Radiotherapy

Modern radiotherapy techniques are designed to permit reduced irradiation of healthy tissue, resulting in a diminished risk of adverse effects and shortened recovery times. Several randomized studies have demonstrated the benefits of increased dosage to the tumor bed area in combination with whole b...

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Bibliographic Details
Published in:Cancers 2022-12, Vol.15 (1), p.298
Main Authors: Kolářová, Iveta, Melichar, Bohuslav, Vaňásek, Jaroslav, Sirák, Igor, Petera, Jiří, Horáčková, Kateřina, Pohanková, Denisa, Šinkorová, Zuzana, Hošek, Oldřich, Vošmik, Milan
Format: Article
Language:English
Subjects:
Adjuvant treatment
Age
Brachytherapy
Breast cancer
Breast carcinoma
Cancer
Cancer therapies
Care and treatment
Chemotherapy
Chronic toxicity
Dosage
Drug dosages
Fractionation
Kinases
Methods
Patients
Radiation therapy
Radiotherapy
Reconstructive surgery
Review
Tumors
Womens health
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Summary:Modern radiotherapy techniques are designed to permit reduced irradiation of healthy tissue, resulting in a diminished risk of adverse effects and shortened recovery times. Several randomized studies have demonstrated the benefits of increased dosage to the tumor bed area in combination with whole breast irradiation (WBI). Conventional WBI treatment following breast-conserving procedures, which required 5-7 weeks of daily treatments, has been reduced to 3-4 weeks when using hyperfractionated regimens. The dosage administration improves local control, albeit with poorer cosmesis. The method of accelerated partial breast irradiation (APBI) shortens the treatment period whilst reducing the irradiated volume. APBI can be delivered using intraoperative radiation, brachytherapy, or external beam radiotherapy. Currently available data support the use of external beam partial breast irradiation in selected patients. Modern radiotherapy techniques make it possible to achieve favorable cosmesis in most patients undergoing immediate breast reconstruction surgery, and studies confirm that current methods of external beam radiation allow an acceptable coverage of target volumes both in the reconstructed breast and in the regional lymphatic nodes.
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers15010298