Hypofractionation as a solution to radiotherapy access in latin america: expert perspective

• Published in: Reports of practical oncology and radiotherapy 2022, Vol.27 (6), p.1094-1105
• Main Authors: Santos, Marcos, Chavez-Nogueda, Jessica, Galvis, Juan Carlos, Merino, Tomas, Oliveira E Silva, Luis, Rico, Mariana, Sarria, Gustavo, Sisamon, Ignacio, Garay, Onix
• Format: Article
• Language: English
• Subjects: Review
• ISSN: 1507-1367; 2083-4640
• DOI: 10.5603/RPOR.a2022.0108

Limited radiation therapy resources have resulted in an interest in developing time and cost-saving innovations to expand access to cancer treatment, in Latin America. Therefore, hypofractionated radiotherapy (HRT) is a possible solution, as this modality delivers radiation over a shorter period of time. A selected panel of Latin American (LA) experts in fields related to HRT were provided with a series of relevant questions to address, prior to the multi-day conference. Within this meeting, each narrative was discussed and edited, through numerous rounds of discussion, until agreement was achieved. The challenges identified in increasing the adoption of HRT in LA include a lack of national and regional clinical practice guidelines and cancer registries; a lack of qualified human resources and personnel education; high up-front costs of equipment; disparate resource distribution and scarce HRT research. An analysis for these overarching challenges was developed and answered with recommendations. Extending the adoption of HRT in LA can provide a path forward to increase access to radiotherapy and overcome the shortage of equipment. HRT has the potential to improve population health outcomes and patient centered care, while offering comparable local control, toxicity, palliation, and late effects for multiple indications, when compared to conventional RT. Concerted efforts from all involved stakeholders are needed to overcome the barriers in adopting this strategy in LA countries. The recommendations presented in this article can serve as a plan of action for HRT adoption in other countries in a similar situation.