Loading…
Low-dose CT from myocardial perfusion SPECT/CT allows the detection of anemia in preoperative patients
To assess whether low-dose CT for attenuation correction of myocardial perfusion single-photon emission computed tomography (SPECT) allows for identification of anemic patients and grading anemia severity. Patients who underwent a preoperative blood-test and low-dose CT scan, as a part of a cardiac...
Saved in:
| Published in: | Journal of nuclear cardiology 2022-12, Vol.29 (6), p.3236-3247 |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c527t-551a2339c71cd0c5b76e0d738563a849e5baa7801a07d7ecd8b703060760ee073 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c527t-551a2339c71cd0c5b76e0d738563a849e5baa7801a07d7ecd8b703060760ee073 |
| container_end_page | 3247 |
| container_issue | 6 |
| container_start_page | 3236 |
| container_title | Journal of nuclear cardiology |
| container_volume | 29 |
| creator | Gennari, Antonio G. Grünig, Hannes Benz, Dominik C. Skawran, Stephan Maurer, Alexander Abukwaik, Ahmad M.A. Rossi, Alexia Gebhard, Catherine Buechel, Ronny R. Messerli, Michael |
| description | To assess whether low-dose CT for attenuation correction of myocardial perfusion single-photon emission computed tomography (SPECT) allows for identification of anemic patients and grading anemia severity.
Patients who underwent a preoperative blood-test and low-dose CT scan, as a part of a cardiac SPECT exam, between 01 January 2015 and 31 December 2017 were enrolled in this retrospective study. Hemoglobin (Hb) levels and hematocrit were derived from clinical records. CT images were visually assessed (qualitative analysis) for the detection of inter-ventricular septum sign (IVSS) and aortic rim sign (ARS) and quantitative analysis were performed. The diagnostic accuracy for detecting anemia was compared using Hb values as the standard of reference. A total of 229 patients were included (110 with anemia; 57 mild; 46 moderate; 7 severe). The AUC of IVSS and ARS were 0.830 and 0.669, respectively (p |
| doi_str_mv | 10.1007/s12350-021-02899-x |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9834113</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1071358123006918</els_id><sourcerecordid>2764469662</sourcerecordid><originalsourceid>FETCH-LOGICAL-c527t-551a2339c71cd0c5b76e0d738563a849e5baa7801a07d7ecd8b703060760ee073</originalsourceid><addsrcrecordid>eNp9kU1r3DAQhk1padK0f6CHIuilFzcjaSVZUAphST9goYVuz0IrjRMF23Ile5P8-2rrNP045CBGMO_7zgxPVb2k8JYCqNNMGRdQA6PlNVrXN4-qYyo4q6UQ9HH5g6I1Fw09qp7lfAUAmmv9tDrigiohhDyu2k28rn3MSNZb0qbYk_42Opt8sB0ZMbVzDnEg376er7enRWK7Ll5nMl0i8Tihmw7d2BI7YB8sCQMZE8ZitFPYIxlLwWHKz6snre0yvrirJ9X3D-fb9ad68-Xj5_XZpnaCqakua1vGuXaKOg9O7JRE8Io3QnLbrDSKnbWqAWpBeYXONzsFHCQoCYig-En1fskd512P3pXZyXZmTKG36dZEG8y_nSFcmou4N7rhK0p5CXhzF5DijxnzZPqQHXZdOTDO2TDJdCNEww-zXv8nvYpzGsp5him5WkktJSsqtqhcijknbO-XoWAOGM2C0RSM5hdGc1NMr_4-497ym1sR8EWQS2u4wPRn9oOx7xYXFgT7UFzZFTwOfUgFpfExPGT_CcwXvPA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2764469662</pqid></control><display><type>article</type><title>Low-dose CT from myocardial perfusion SPECT/CT allows the detection of anemia in preoperative patients</title><source>Springer Nature</source><creator>Gennari, Antonio G. ; Grünig, Hannes ; Benz, Dominik C. ; Skawran, Stephan ; Maurer, Alexander ; Abukwaik, Ahmad M.A. ; Rossi, Alexia ; Gebhard, Catherine ; Buechel, Ronny R. ; Messerli, Michael</creator><creatorcontrib>Gennari, Antonio G. ; Grünig, Hannes ; Benz, Dominik C. ; Skawran, Stephan ; Maurer, Alexander ; Abukwaik, Ahmad M.A. ; Rossi, Alexia ; Gebhard, Catherine ; Buechel, Ronny R. ; Messerli, Michael</creatorcontrib><description>To assess whether low-dose CT for attenuation correction of myocardial perfusion single-photon emission computed tomography (SPECT) allows for identification of anemic patients and grading anemia severity.
Patients who underwent a preoperative blood-test and low-dose CT scan, as a part of a cardiac SPECT exam, between 01 January 2015 and 31 December 2017 were enrolled in this retrospective study. Hemoglobin (Hb) levels and hematocrit were derived from clinical records. CT images were visually assessed (qualitative analysis) for the detection of inter-ventricular septum sign (IVSS) and aortic rim sign (ARS) and quantitative analysis were performed. The diagnostic accuracy for detecting anemia was compared using Hb values as the standard of reference. A total of 229 patients were included (110 with anemia; 57 mild; 46 moderate; 7 severe). The AUC of IVSS and ARS were 0.830 and 0.669, respectively (p<0.0001). The quantitative analysis outperformed ARS and IVSS; (AUC of 0.893, p=0.29). The optimal anemia cut-off using Youden index was 4.5 HU.
Quantitative analysis derived from low-dose CT images, as a part of cardiac SPECT exams, have a diagnostic accuracy similar to that of hematocrit for the detection of anemia and may allow discriminating different anemia severities.
▪</description><identifier>ISSN: 1071-3581</identifier><identifier>EISSN: 1532-6551</identifier><identifier>DOI: 10.1007/s12350-021-02899-x</identifier><identifier>PMID: 35175556</identifier><language>eng</language><publisher>Cham: Elsevier Inc</publisher><subject>Anemia ; Anemia - diagnostic imaging ; Cardiology ; Emission-computed ; Hematocrit ; Hemoglobin ; Humans ; Imaging ; Medicine ; Medicine & Public Health ; Myocardial Perfusion Imaging - methods ; Nuclear Medicine ; Original ; Original Article ; Perfusion ; Quantitative analysis ; Radiology ; Retrospective Studies ; Sensitivity and Specificity ; Single-photon ; Tomography ; Tomography, Emission-Computed, Single-Photon - methods ; Tomography, X-Ray Computed - methods ; X-ray computed</subject><ispartof>Journal of nuclear cardiology, 2022-12, Vol.29 (6), p.3236-3247</ispartof><rights>2022 THE AUTHORS. Published by ELSEVIER INC. on behalf of American Society of Nuclear Cardiology</rights><rights>The Author(s) 2022</rights><rights>2022. The Author(s).</rights><rights>The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c527t-551a2339c71cd0c5b76e0d738563a849e5baa7801a07d7ecd8b703060760ee073</citedby><cites>FETCH-LOGICAL-c527t-551a2339c71cd0c5b76e0d738563a849e5baa7801a07d7ecd8b703060760ee073</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35175556$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gennari, Antonio G.</creatorcontrib><creatorcontrib>Grünig, Hannes</creatorcontrib><creatorcontrib>Benz, Dominik C.</creatorcontrib><creatorcontrib>Skawran, Stephan</creatorcontrib><creatorcontrib>Maurer, Alexander</creatorcontrib><creatorcontrib>Abukwaik, Ahmad M.A.</creatorcontrib><creatorcontrib>Rossi, Alexia</creatorcontrib><creatorcontrib>Gebhard, Catherine</creatorcontrib><creatorcontrib>Buechel, Ronny R.</creatorcontrib><creatorcontrib>Messerli, Michael</creatorcontrib><title>Low-dose CT from myocardial perfusion SPECT/CT allows the detection of anemia in preoperative patients</title><title>Journal of nuclear cardiology</title><addtitle>J. Nucl. Cardiol</addtitle><addtitle>J Nucl Cardiol</addtitle><description>To assess whether low-dose CT for attenuation correction of myocardial perfusion single-photon emission computed tomography (SPECT) allows for identification of anemic patients and grading anemia severity.
Patients who underwent a preoperative blood-test and low-dose CT scan, as a part of a cardiac SPECT exam, between 01 January 2015 and 31 December 2017 were enrolled in this retrospective study. Hemoglobin (Hb) levels and hematocrit were derived from clinical records. CT images were visually assessed (qualitative analysis) for the detection of inter-ventricular septum sign (IVSS) and aortic rim sign (ARS) and quantitative analysis were performed. The diagnostic accuracy for detecting anemia was compared using Hb values as the standard of reference. A total of 229 patients were included (110 with anemia; 57 mild; 46 moderate; 7 severe). The AUC of IVSS and ARS were 0.830 and 0.669, respectively (p<0.0001). The quantitative analysis outperformed ARS and IVSS; (AUC of 0.893, p=0.29). The optimal anemia cut-off using Youden index was 4.5 HU.
Quantitative analysis derived from low-dose CT images, as a part of cardiac SPECT exams, have a diagnostic accuracy similar to that of hematocrit for the detection of anemia and may allow discriminating different anemia severities.
▪</description><subject>Anemia</subject><subject>Anemia - diagnostic imaging</subject><subject>Cardiology</subject><subject>Emission-computed</subject><subject>Hematocrit</subject><subject>Hemoglobin</subject><subject>Humans</subject><subject>Imaging</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Myocardial Perfusion Imaging - methods</subject><subject>Nuclear Medicine</subject><subject>Original</subject><subject>Original Article</subject><subject>Perfusion</subject><subject>Quantitative analysis</subject><subject>Radiology</subject><subject>Retrospective Studies</subject><subject>Sensitivity and Specificity</subject><subject>Single-photon</subject><subject>Tomography</subject><subject>Tomography, Emission-Computed, Single-Photon - methods</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>X-ray computed</subject><issn>1071-3581</issn><issn>1532-6551</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><recordid>eNp9kU1r3DAQhk1padK0f6CHIuilFzcjaSVZUAphST9goYVuz0IrjRMF23Ile5P8-2rrNP045CBGMO_7zgxPVb2k8JYCqNNMGRdQA6PlNVrXN4-qYyo4q6UQ9HH5g6I1Fw09qp7lfAUAmmv9tDrigiohhDyu2k28rn3MSNZb0qbYk_42Opt8sB0ZMbVzDnEg376er7enRWK7Ll5nMl0i8Tihmw7d2BI7YB8sCQMZE8ZitFPYIxlLwWHKz6snre0yvrirJ9X3D-fb9ad68-Xj5_XZpnaCqakua1vGuXaKOg9O7JRE8Io3QnLbrDSKnbWqAWpBeYXONzsFHCQoCYig-En1fskd512P3pXZyXZmTKG36dZEG8y_nSFcmou4N7rhK0p5CXhzF5DijxnzZPqQHXZdOTDO2TDJdCNEww-zXv8nvYpzGsp5him5WkktJSsqtqhcijknbO-XoWAOGM2C0RSM5hdGc1NMr_4-497ym1sR8EWQS2u4wPRn9oOx7xYXFgT7UFzZFTwOfUgFpfExPGT_CcwXvPA</recordid><startdate>20221201</startdate><enddate>20221201</enddate><creator>Gennari, Antonio G.</creator><creator>Grünig, Hannes</creator><creator>Benz, Dominik C.</creator><creator>Skawran, Stephan</creator><creator>Maurer, Alexander</creator><creator>Abukwaik, Ahmad M.A.</creator><creator>Rossi, Alexia</creator><creator>Gebhard, Catherine</creator><creator>Buechel, Ronny R.</creator><creator>Messerli, Michael</creator><general>Elsevier Inc</general><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>6I.</scope><scope>AAFTH</scope><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20221201</creationdate><title>Low-dose CT from myocardial perfusion SPECT/CT allows the detection of anemia in preoperative patients</title><author>Gennari, Antonio G. ; Grünig, Hannes ; Benz, Dominik C. ; Skawran, Stephan ; Maurer, Alexander ; Abukwaik, Ahmad M.A. ; Rossi, Alexia ; Gebhard, Catherine ; Buechel, Ronny R. ; Messerli, Michael</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c527t-551a2339c71cd0c5b76e0d738563a849e5baa7801a07d7ecd8b703060760ee073</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Anemia</topic><topic>Anemia - diagnostic imaging</topic><topic>Cardiology</topic><topic>Emission-computed</topic><topic>Hematocrit</topic><topic>Hemoglobin</topic><topic>Humans</topic><topic>Imaging</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Myocardial Perfusion Imaging - methods</topic><topic>Nuclear Medicine</topic><topic>Original</topic><topic>Original Article</topic><topic>Perfusion</topic><topic>Quantitative analysis</topic><topic>Radiology</topic><topic>Retrospective Studies</topic><topic>Sensitivity and Specificity</topic><topic>Single-photon</topic><topic>Tomography</topic><topic>Tomography, Emission-Computed, Single-Photon - methods</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>X-ray computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gennari, Antonio G.</creatorcontrib><creatorcontrib>Grünig, Hannes</creatorcontrib><creatorcontrib>Benz, Dominik C.</creatorcontrib><creatorcontrib>Skawran, Stephan</creatorcontrib><creatorcontrib>Maurer, Alexander</creatorcontrib><creatorcontrib>Abukwaik, Ahmad M.A.</creatorcontrib><creatorcontrib>Rossi, Alexia</creatorcontrib><creatorcontrib>Gebhard, Catherine</creatorcontrib><creatorcontrib>Buechel, Ronny R.</creatorcontrib><creatorcontrib>Messerli, Michael</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Springer_OA刊</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of nuclear cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gennari, Antonio G.</au><au>Grünig, Hannes</au><au>Benz, Dominik C.</au><au>Skawran, Stephan</au><au>Maurer, Alexander</au><au>Abukwaik, Ahmad M.A.</au><au>Rossi, Alexia</au><au>Gebhard, Catherine</au><au>Buechel, Ronny R.</au><au>Messerli, Michael</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Low-dose CT from myocardial perfusion SPECT/CT allows the detection of anemia in preoperative patients</atitle><jtitle>Journal of nuclear cardiology</jtitle><stitle>J. Nucl. Cardiol</stitle><addtitle>J Nucl Cardiol</addtitle><date>2022-12-01</date><risdate>2022</risdate><volume>29</volume><issue>6</issue><spage>3236</spage><epage>3247</epage><pages>3236-3247</pages><issn>1071-3581</issn><eissn>1532-6551</eissn><abstract>To assess whether low-dose CT for attenuation correction of myocardial perfusion single-photon emission computed tomography (SPECT) allows for identification of anemic patients and grading anemia severity.
Patients who underwent a preoperative blood-test and low-dose CT scan, as a part of a cardiac SPECT exam, between 01 January 2015 and 31 December 2017 were enrolled in this retrospective study. Hemoglobin (Hb) levels and hematocrit were derived from clinical records. CT images were visually assessed (qualitative analysis) for the detection of inter-ventricular septum sign (IVSS) and aortic rim sign (ARS) and quantitative analysis were performed. The diagnostic accuracy for detecting anemia was compared using Hb values as the standard of reference. A total of 229 patients were included (110 with anemia; 57 mild; 46 moderate; 7 severe). The AUC of IVSS and ARS were 0.830 and 0.669, respectively (p<0.0001). The quantitative analysis outperformed ARS and IVSS; (AUC of 0.893, p=0.29). The optimal anemia cut-off using Youden index was 4.5 HU.
Quantitative analysis derived from low-dose CT images, as a part of cardiac SPECT exams, have a diagnostic accuracy similar to that of hematocrit for the detection of anemia and may allow discriminating different anemia severities.
▪</abstract><cop>Cham</cop><pub>Elsevier Inc</pub><pmid>35175556</pmid><doi>10.1007/s12350-021-02899-x</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1071-3581 |
| ispartof | Journal of nuclear cardiology, 2022-12, Vol.29 (6), p.3236-3247 |
| issn | 1071-3581 1532-6551 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9834113 |
| source | Springer Nature |
| subjects | Anemia Anemia - diagnostic imaging Cardiology Emission-computed Hematocrit Hemoglobin Humans Imaging Medicine Medicine & Public Health Myocardial Perfusion Imaging - methods Nuclear Medicine Original Original Article Perfusion Quantitative analysis Radiology Retrospective Studies Sensitivity and Specificity Single-photon Tomography Tomography, Emission-Computed, Single-Photon - methods Tomography, X-Ray Computed - methods X-ray computed |
| title | Low-dose CT from myocardial perfusion SPECT/CT allows the detection of anemia in preoperative patients |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T18%3A36%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Low-dose%20CT%20from%20myocardial%20perfusion%20SPECT/CT%20allows%20the%20detection%20of%20anemia%20in%20preoperative%20patients&rft.jtitle=Journal%20of%20nuclear%20cardiology&rft.au=Gennari,%20Antonio%20G.&rft.date=2022-12-01&rft.volume=29&rft.issue=6&rft.spage=3236&rft.epage=3247&rft.pages=3236-3247&rft.issn=1071-3581&rft.eissn=1532-6551&rft_id=info:doi/10.1007/s12350-021-02899-x&rft_dat=%3Cproquest_pubme%3E2764469662%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c527t-551a2339c71cd0c5b76e0d738563a849e5baa7801a07d7ecd8b703060760ee073%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2764469662&rft_id=info:pmid/35175556&rfr_iscdi=true |