Trends in Overall and Micronutrient-Containing Dietary Supplement Use in US Adults and Children, NHANES 2007–2018

• Published in: The Journal of nutrition 2022-12, Vol.152 (12), p.2789-2801
• Main Authors: Cowan, Alexandra E, Tooze, Janet A, Gahche, Jaime J, Eicher-Miller, Heather A, Guenther, Patricia M, Dwyer, Johanna T, Potischman, Nancy, Bhadra, Anindya, Carroll, Raymond J, Bailey, Regan L
• Format: Article
• Language: English
• Subjects: Adult; Adults; Child; Children; Diet; dietary assessment; dietary supplement; Dietary Supplements; Food security; Humans; Income; Magnesium; Male; Micronutrients; NHANES; nutrient intake; Nutrients; Nutrition; Nutrition Surveys; Nutritional Epidemiology; Polynomials; Poverty; Prescription drugs; Subgroups; Trace Elements; Trends; United States; Vitamin D; Vitamins
• ISSN: 0022-3166; 1541-6100
• DOI: 10.1093/jn/nxac168

Dietary supplement (DS) use is widespread in the United States and contributes large amounts of micronutrients to users. Most studies have relied on data from 1 assessment method to characterize the prevalence of DS use. Combining multiple methods enhances the ability to capture nutrient exposures from DSs and examine trends over time. The objective of this study was to characterize DS use and examine trends in any DS as well as micronutrient-containing (MN) DS use in a nationally representative sample of the US population (≥1 y) from the 2007–2018 NHANES using a combined approach. NHANES obtains an in-home inventory with a frequency-based dietary supplement and prescription medicine questionnaire (DSMQ), and two 24-h dietary recalls (24HRs). Trends in the prevalence of use and selected types of products used were estimated for the population and by sex, age, race/Hispanic origin, family income [poverty-to-income ratio (PIR)], and household food security (food-secure vs. food-insecure) using the DSMQ or ≥ 1 24HR. Linear trends were tested using orthogonal polynomials (significance set at P < 0.05). DS use increased from 50% in 2007 to 56% in 2018 (P = 0.001); use of MN products increased from 46% to 49% (P = 0.03), and single-nutrient DS (e.g., magnesium, vitamins B-12 and D) use also increased (all P < 0.001). In contrast, multivitamin-mineral use decreased (70% to 56%; P < 0.001). In adults (≥19 y), any (54% to 61%) and MN (49% to 54%) DS use increased, especially in men, non-Hispanic blacks and Hispanics, and low-income adults (PIR ≤130%). In children (1–18 y), any DS use remained stable (∼38%), as did MN use, except for food-insecure children, whose use increased from 24% to 31% over the decade (P = 0.03). The prevalence of any and MN DS use increased over time in the United States. This may be partially attributed to increased use of single-nutrient products. Population subgroups differed in their DS use.