Occupational Lung Disease Caused by Exposure to Polytetrafluoroethylene

We herein report a 45-year-old-man with multiple foreign body granulomas in the lungs caused by polytetrafluoroethylene (PTFE). A mass in the right lower lobe of the lung and bilateral centrilobular lung nodules were found unexpectedly during the patient's visit to a hospital for a respiratory...

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Bibliographic Details
Published in:Internal medicine (Tokyo, 1992) 1992), 2022-12, Vol.61 (24), p.3713-3717, Article 9008-21
Main Authors: Aoki, Ami, Saito, Akira, Shima, Kenjiro, Kimura, Yosuke, Asakawa, Katsuaki, Ohashi, Riuko, Umezu, Hajime, Sakagami, Takuro, Moriyama, Hiroshi, Kikuchi, Toshiaki
Format: Article
Language:English
Subjects:
Biopsy
Bronchoscopy
Case Report
Electron probe
Fluorine
Giant cells
Granuloma - pathology
Humans
Internal medicine
Lung - diagnostic imaging
Lung - pathology
Lung diseases
Lung Diseases - etiology
Lung Diseases - pathology
Lung nodules
Middle Aged
Occupational Diseases - complications
Occupational exposure
Polytetrafluoroethylene
Polytetrafluoroethylene - adverse effects
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Summary:We herein report a 45-year-old-man with multiple foreign body granulomas in the lungs caused by polytetrafluoroethylene (PTFE). A mass in the right lower lobe of the lung and bilateral centrilobular lung nodules were found unexpectedly during the patient's visit to a hospital for a respiratory infection. The patient's occupation for 26 years involved spraying PTFE. A lung biopsy using bronchoscopy revealed granulomatous lesions and giant cells. The presence of fluorine in the granulomatous lesions was confirmed using an electron probe microanalyzer with wavelength dispersive spectrometer. Fluorine is a component of PTFE and is not found in normal lung tissue.
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.9008-21