P-Wave Duration and Interatrial Conduction Abnormalities in Paroxysmal and Persistent Typical Atrial Flutter

• Published in: Physiological research 2022-11, Vol.71 (5), p.597-606
• Main Authors: ŚLIMAK, J, MERCIK, J, UNKELL, M, ZAWADZKI, G, RADZIEJEWSKA, J, GAJEK, J
• Format: Article
• Language: English
• Subjects: Ablation; Age; Arrhythmia; Cardiac arrhythmia; Comorbidity; Creatinine; Disease; EKG; Morphology; Pathology; Population studies; Sinuses; Statistical analysis; Structure-function relationships
• ISSN: 0862-8408; 1802-9973
• DOI: 10.33549/physiolres.934731

Functional and structural changes, the enlargement of the right atrium is the background for the development of typical atrial flutter (AFL). These changes in ECG are manifested in the morphology of the initial part of the P-wave. The aim of the study was to assess the duration and morphology of the P-wave in patients with paroxysmal and persistent AFL. The study population consisted of 131 patients with AFL, 38 women and 93 men aged 66 years (60-72), divided in 62 patients with paroxysmal and 69 with persistent AFL. P-wave duration was measured with an electrophysiological system in all leads at a paper speed of 200 mm/s. The groups did differ in terms of gender (38/24 vs. 55/14, (M/F), p=0.033). Patients with persistent AF had a longer P-wave duration – 175±26.3 ms vs. 159±22.6 ms, p=0.01, and higher creatinine concentration – 1.2±0.60 mg/dl vs. 1.08±0.68 mg/dl, p=0.007. The presence and severity of interatrial conduction block (I-none, II-partial, III-total) was related to age of the patients (60.3±12.1 vs. 64.7±-8.3 vs. 68.9±9.5 years, respectively). Patients with persistent AFL show a longer P-wave compared to paroxysmal AFL, regardless of comorbidities and antiarrhythmic drugs. The arrhythmia-related longer P-wave duration should encourage the clinicians to restore sinus rhythm earlier in order to more effectively maintain it over the long term.