Uveitis in psoriatic arthritis: study of 406 patients in a single university center and literature review

• Published in: Rheumatic & musculoskeletal diseases open 2023-01, Vol.9 (1), p.e002781
• Main Authors: De Vicente Delmás, Ana, Sanchez-Bilbao, Lara, Calvo-Río, Vanesa, Martínez-López, David, Herrero-Morant, Alba, Galíndez-Agirregoikoa, Eva, Gonzalez-Mazon, Iñigo, Barroso-García, Nuria, Palmou-Fontana, Natalia, Gonzalez-Gay, Miguel A, Hernández, José L, Blanco, Ricardo
• Format: Article
• Language: English
• Subjects: Arthritis, Psoriatic - complications; Arthritis, Psoriatic - diagnosis; Arthritis, Psoriatic - drug therapy; Etanercept - therapeutic use; Humans; Longitudinal Studies; Psoriatic Arthritis; Quality of Life; Retrospective Studies; Universities; Uveitis - diagnosis; Uveitis - drug therapy; Uveitis - epidemiology
• ISSN: 2056-5933; 2056-5933
• DOI: 10.1136/rmdopen-2022-002781

The manifestations of uveitis are well established in axial spondyloarthritis (ax-SpA), but not in psoriatic arthritis (PsA). We aimed to assess, in a large unselected series of PsA: (A) the frequency and clinical features of uveitis; (B) its association with PsA activity, the impact of disease and functional disability, and (C) its relationship with the biological treatment. In addition, a literature review was performed. Retrospective longitudinal study of PsA patients from a single referral hospital. PsA was classified according to the CASPAR criteria, and uveitis was diagnosed by experienced ophthalmologists. We studied 406 patients with PsA (46.3±12.3 years). Uveitis was observed in 20 (4.9%). Uveitis was acute in all cases, anterior (80%), unilateral (80%) and recurrent (50%). Patients with uveitis had a higher prevalence of HLA-B27 (45% vs 7.5%, p