AngioDB: database of angiogenesis and angiogenesis-related molecules

Angiogenesis is the formation of new capillaries sprouting from pre-existing vessels. Angiogenesis occurs in a variety of normal physiological and pathological conditions and is regulated by a balance of stimulatory and inhibitory angiogenic factors. The control of this balance may fail and result i...

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Bibliographic Details
Published in:Nucleic acids research 2002-01, Vol.30 (1), p.369-371
Main Authors: Sohn, Tae-Kwon, Moon, Eun-Joung, Lee, Seok-Ki, Cho, Hwan-Gue, Kim, Kyu-Won
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Angiogenesis Inducing Agents - classification
Angiogenesis Inducing Agents - genetics
Angiogenesis Inhibitors - classification
Angiogenesis Inhibitors - genetics
Base Sequence
Computer Graphics
Databases, Protein
Forecasting
Humans
Information Storage and Retrieval
Internet
Neovascularization, Pathologic
Neovascularization, Physiologic
Signal Transduction
Systems Integration
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Summary:Angiogenesis is the formation of new capillaries sprouting from pre-existing vessels. Angiogenesis occurs in a variety of normal physiological and pathological conditions and is regulated by a balance of stimulatory and inhibitory angiogenic factors. The control of this balance may fail and result in the formation of a pathologic capillary network during the development of many diseases. Therefore, we developed the angiogenesis database (AngioDB), which can provide a signaling network of angiogenesis-related biomolecules in human. Each record of AngioDB consisted of 12 fields and was developed by using a relational database management system. For the retrieval of data, Active Server Page (ASP) technology was integrated in this system. Users can access the database by a query or imagemap browsing program. The retrieving system also provides a list of angiogenesis-related molecules classified by three categories, and the database has an external link to NCBI databases. AngioDB is available via the Internet at http://angiodb.snu.ac.kr/.
ISSN:1362-4962
0305-1048
1362-4962
DOI:10.1093/nar/30.1.369