KIR-favorable TCR-αβ/CD19-depleted haploidentical HCT in children with ALL/AML/MDS: primary analysis of the PTCTC ONC1401 trial

•Two-year DFS/OS of children with leukemia/MDS (MRD

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Bibliographic Details
Published in:Blood 2022-12, Vol.140 (24), p.2556-2572
Main Authors: Pulsipher, Michael A., Ahn, Kwang W., Bunin, Nancy J., Lalefar, Nahal, Anderson, Eric, Flower, Allyson, Cairo, Mitchell S., Talano, Julie-An, Chaudhury, Sonali, Kitko, Carrie L., Duke, Jamie L., Monos, Dimitrios, Leung, Wing, Dvorak, Christopher C., Abdel-Azim, Hisham
Format: Article
Language:English
Subjects:
Antigens, CD19
Child
Graft vs Host Disease - etiology
Hematopoietic Stem Cell Transplantation
Humans
Leukemia, Myeloid, Acute - therapy
Myelodysplastic Syndromes - therapy
Prospective Studies
Receptors, Antigen, T-Cell, alpha-beta
Receptors, KIR
Regular
Transplantation Conditioning
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Description
Summary:•Two-year DFS/OS of children with leukemia/MDS (MRD
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.2022015959