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Visual Inspection for Lower Limb Malalignment Diagnosis Is Unreliable

Objective Visual inspection of the lower limb is often part of standard clinical practice during a physical examination at the outpatient clinic. This study aims to investigate how reliable visual inspections are in terms of detecting lower limb malalignments without additional tools and physical ex...

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Published in:Cartilage 2022-12, Vol.13 (4), p.59-65
Main Authors: Nguyen, H. Chien, van Egmond, Nienke, de Visser, Huub M., Weinans, Harrie, Sakkers, Ralph J.B., Custers, Roel J.H.
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container_title Cartilage
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creator Nguyen, H. Chien
van Egmond, Nienke
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description Objective Visual inspection of the lower limb is often part of standard clinical practice during a physical examination at the outpatient clinic. This study aims to investigate how reliable visual inspections are in terms of detecting lower limb malalignments without additional tools and physical examinations. Design This study enrolled 50 patients. Each patient underwent a whole leg radiograph (WLR); in addition, a standardized digital photograph was taken of the lower limbs. Four persons (different experience levels) visually rated the digital photograph twice (unaware of the hip knee angle [HKA] on the WLR) and placed them in the category: severe valgus (>5°); moderate valgus (2°-5°); neutral, moderate varus (2°-5°); and severe varus (>5°). Visual ratings were compared with the measured HKA on WLRs for correlation using Spearman’s rho. Linear ordinal regression models with significance when P < 0.05 were used to test whether body mass index (BMI), age, gender, and HKA were possible risk factors for incorrect visual HKA assessment. Results Spearman’s rho between the visual assessment and measured HKA on the WLR was moderate with 0.478 (P < 0.01). Women had an increased odds ratio of 3.7 (P = 0.001) for incorrect visual assessment. Higher HKA also increased the odds ratio for erroneous visual assessment with 1.4 (P = 0.003). BMI and age did not significantly increase the odds of erroneous visual leg axis assessments in this study. Conclusions Visual assessment of the lower limb alignment does not provide clinically relevant information. Lower limb malalignment diagnoses cannot be performed using only a visual inspection. Physical examination tests and radiographical assessments are advised. Level of evidence: Diagnostic level II
doi_str_mv 10.1177/19476035221113952
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Chien ; van Egmond, Nienke ; de Visser, Huub M. ; Weinans, Harrie ; Sakkers, Ralph J.B. ; Custers, Roel J.H.</creator><creatorcontrib>Nguyen, H. Chien ; van Egmond, Nienke ; de Visser, Huub M. ; Weinans, Harrie ; Sakkers, Ralph J.B. ; Custers, Roel J.H.</creatorcontrib><description>Objective Visual inspection of the lower limb is often part of standard clinical practice during a physical examination at the outpatient clinic. This study aims to investigate how reliable visual inspections are in terms of detecting lower limb malalignments without additional tools and physical examinations. Design This study enrolled 50 patients. Each patient underwent a whole leg radiograph (WLR); in addition, a standardized digital photograph was taken of the lower limbs. Four persons (different experience levels) visually rated the digital photograph twice (unaware of the hip knee angle [HKA] on the WLR) and placed them in the category: severe valgus (&gt;5°); moderate valgus (2°-5°); neutral, moderate varus (2°-5°); and severe varus (&gt;5°). Visual ratings were compared with the measured HKA on WLRs for correlation using Spearman’s rho. Linear ordinal regression models with significance when P &lt; 0.05 were used to test whether body mass index (BMI), age, gender, and HKA were possible risk factors for incorrect visual HKA assessment. Results Spearman’s rho between the visual assessment and measured HKA on the WLR was moderate with 0.478 (P &lt; 0.01). Women had an increased odds ratio of 3.7 (P = 0.001) for incorrect visual assessment. Higher HKA also increased the odds ratio for erroneous visual assessment with 1.4 (P = 0.003). BMI and age did not significantly increase the odds of erroneous visual leg axis assessments in this study. Conclusions Visual assessment of the lower limb alignment does not provide clinically relevant information. Lower limb malalignment diagnoses cannot be performed using only a visual inspection. Physical examination tests and radiographical assessments are advised. Level of evidence: Diagnostic level II</description><identifier>ISSN: 1947-6035</identifier><identifier>EISSN: 1947-6043</identifier><identifier>DOI: 10.1177/19476035221113952</identifier><identifier>PMID: 36305650</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Clinical s ; Female ; Humans ; Knee Joint - diagnostic imaging ; Lower Extremity ; Osteoarthritis, Knee ; Physical Examination ; Retrospective Studies</subject><ispartof>Cartilage, 2022-12, Vol.13 (4), p.59-65</ispartof><rights>The Author(s) 2022</rights><rights>The Author(s) 2022 2022 SAGE Publications Ltd unless otherwise noted. Manuscript content on this site is licensed under Creative Commons Licenses</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c504t-52cc3e23ae3a53d4641b02e013cc6f77c4fe2de7adfe25ec47cb48f3eedc767c3</citedby><cites>FETCH-LOGICAL-c504t-52cc3e23ae3a53d4641b02e013cc6f77c4fe2de7adfe25ec47cb48f3eedc767c3</cites><orcidid>0000-0001-5436-7981</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924985/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9924985/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,21966,27853,27924,27925,44945,45333,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36305650$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nguyen, H. Chien</creatorcontrib><creatorcontrib>van Egmond, Nienke</creatorcontrib><creatorcontrib>de Visser, Huub M.</creatorcontrib><creatorcontrib>Weinans, Harrie</creatorcontrib><creatorcontrib>Sakkers, Ralph J.B.</creatorcontrib><creatorcontrib>Custers, Roel J.H.</creatorcontrib><title>Visual Inspection for Lower Limb Malalignment Diagnosis Is Unreliable</title><title>Cartilage</title><addtitle>Cartilage</addtitle><description>Objective Visual inspection of the lower limb is often part of standard clinical practice during a physical examination at the outpatient clinic. This study aims to investigate how reliable visual inspections are in terms of detecting lower limb malalignments without additional tools and physical examinations. Design This study enrolled 50 patients. Each patient underwent a whole leg radiograph (WLR); in addition, a standardized digital photograph was taken of the lower limbs. Four persons (different experience levels) visually rated the digital photograph twice (unaware of the hip knee angle [HKA] on the WLR) and placed them in the category: severe valgus (&gt;5°); moderate valgus (2°-5°); neutral, moderate varus (2°-5°); and severe varus (&gt;5°). Visual ratings were compared with the measured HKA on WLRs for correlation using Spearman’s rho. Linear ordinal regression models with significance when P &lt; 0.05 were used to test whether body mass index (BMI), age, gender, and HKA were possible risk factors for incorrect visual HKA assessment. Results Spearman’s rho between the visual assessment and measured HKA on the WLR was moderate with 0.478 (P &lt; 0.01). Women had an increased odds ratio of 3.7 (P = 0.001) for incorrect visual assessment. Higher HKA also increased the odds ratio for erroneous visual assessment with 1.4 (P = 0.003). BMI and age did not significantly increase the odds of erroneous visual leg axis assessments in this study. Conclusions Visual assessment of the lower limb alignment does not provide clinically relevant information. Lower limb malalignment diagnoses cannot be performed using only a visual inspection. Physical examination tests and radiographical assessments are advised. Level of evidence: Diagnostic level II</description><subject>Clinical s</subject><subject>Female</subject><subject>Humans</subject><subject>Knee Joint - diagnostic imaging</subject><subject>Lower Extremity</subject><subject>Osteoarthritis, Knee</subject><subject>Physical Examination</subject><subject>Retrospective Studies</subject><issn>1947-6035</issn><issn>1947-6043</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>AFRWT</sourceid><recordid>eNp9UE1LAzEQDaL4_QO8yB69VPOd7kUQPwsVL9ZryKazNZJNatJV_PdGWosieJkZ3rx5M_MQOiL4lBClzkjNlcRMUEoIYbWgG2j3CxtIzNnmumZiB-3l_IKxlPVQbKMdJhkWUuBddP3kcm98NQp5DnbhYqjamKpxfIcSXddU98Yb72ahg7CorpyZhZhdrka5moQE3pnGwwHaao3PcLjK-2hyc_14eTcYP9yOLi_GAyswXwwEtZYBZQaYEWzKJScNpoAJs1a2SlneAp2CMtOSBViubMOHLQOYWiWVZfvofKk775uugOWkZLyeJ9eZ9KGjcfp3J7hnPYtvuq4pL68XgZOVQIqvPeSF7ly24L0JEPusqWKYkZoOWaGSJdWmmHOCdr2GYP1lv_5jf5k5_nnfeuLb70I4XRKymYF-iX0Kxa9_FD8BB6COxQ</recordid><startdate>20221201</startdate><enddate>20221201</enddate><creator>Nguyen, H. Chien</creator><creator>van Egmond, Nienke</creator><creator>de Visser, Huub M.</creator><creator>Weinans, Harrie</creator><creator>Sakkers, Ralph J.B.</creator><creator>Custers, Roel J.H.</creator><general>SAGE Publications</general><scope>AFRWT</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-5436-7981</orcidid></search><sort><creationdate>20221201</creationdate><title>Visual Inspection for Lower Limb Malalignment Diagnosis Is Unreliable</title><author>Nguyen, H. Chien ; van Egmond, Nienke ; de Visser, Huub M. ; Weinans, Harrie ; Sakkers, Ralph J.B. ; Custers, Roel J.H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c504t-52cc3e23ae3a53d4641b02e013cc6f77c4fe2de7adfe25ec47cb48f3eedc767c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Clinical s</topic><topic>Female</topic><topic>Humans</topic><topic>Knee Joint - diagnostic imaging</topic><topic>Lower Extremity</topic><topic>Osteoarthritis, Knee</topic><topic>Physical Examination</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nguyen, H. Chien</creatorcontrib><creatorcontrib>van Egmond, Nienke</creatorcontrib><creatorcontrib>de Visser, Huub M.</creatorcontrib><creatorcontrib>Weinans, Harrie</creatorcontrib><creatorcontrib>Sakkers, Ralph J.B.</creatorcontrib><creatorcontrib>Custers, Roel J.H.</creatorcontrib><collection>Sage Journals GOLD Open Access 2024</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Cartilage</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nguyen, H. Chien</au><au>van Egmond, Nienke</au><au>de Visser, Huub M.</au><au>Weinans, Harrie</au><au>Sakkers, Ralph J.B.</au><au>Custers, Roel J.H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Visual Inspection for Lower Limb Malalignment Diagnosis Is Unreliable</atitle><jtitle>Cartilage</jtitle><addtitle>Cartilage</addtitle><date>2022-12-01</date><risdate>2022</risdate><volume>13</volume><issue>4</issue><spage>59</spage><epage>65</epage><pages>59-65</pages><issn>1947-6035</issn><eissn>1947-6043</eissn><abstract>Objective Visual inspection of the lower limb is often part of standard clinical practice during a physical examination at the outpatient clinic. This study aims to investigate how reliable visual inspections are in terms of detecting lower limb malalignments without additional tools and physical examinations. Design This study enrolled 50 patients. Each patient underwent a whole leg radiograph (WLR); in addition, a standardized digital photograph was taken of the lower limbs. Four persons (different experience levels) visually rated the digital photograph twice (unaware of the hip knee angle [HKA] on the WLR) and placed them in the category: severe valgus (&gt;5°); moderate valgus (2°-5°); neutral, moderate varus (2°-5°); and severe varus (&gt;5°). Visual ratings were compared with the measured HKA on WLRs for correlation using Spearman’s rho. Linear ordinal regression models with significance when P &lt; 0.05 were used to test whether body mass index (BMI), age, gender, and HKA were possible risk factors for incorrect visual HKA assessment. Results Spearman’s rho between the visual assessment and measured HKA on the WLR was moderate with 0.478 (P &lt; 0.01). Women had an increased odds ratio of 3.7 (P = 0.001) for incorrect visual assessment. Higher HKA also increased the odds ratio for erroneous visual assessment with 1.4 (P = 0.003). BMI and age did not significantly increase the odds of erroneous visual leg axis assessments in this study. Conclusions Visual assessment of the lower limb alignment does not provide clinically relevant information. Lower limb malalignment diagnoses cannot be performed using only a visual inspection. Physical examination tests and radiographical assessments are advised. Level of evidence: Diagnostic level II</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>36305650</pmid><doi>10.1177/19476035221113952</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0001-5436-7981</orcidid><oa>free_for_read</oa></addata></record>
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source Sage Journals GOLD Open Access 2024; PubMed Central
subjects Clinical s
Female
Humans
Knee Joint - diagnostic imaging
Lower Extremity
Osteoarthritis, Knee
Physical Examination
Retrospective Studies
title Visual Inspection for Lower Limb Malalignment Diagnosis Is Unreliable
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