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Hyperlactatemia and altered lactate kinetics are associated with excess mortality in sepsis: A multicenter retrospective observational study

Summary Severe hyperlactatemia (>10mmol/L) or impaired lactate metabolism are known to correlate with increased mortality. The maximum lactate concentration on day 1 of 10,724 septic patients from the eICU Collaborative Research Database was analyzed and patients were divided into three groups ba...

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Bibliographic Details
Published in:Wiener Klinische Wochenschrift 2023-02, Vol.135 (3-4), p.80-88
Main Authors: Rezar, Richard, Mamandipoor, Behrooz, Seelmaier, Clemens, Jung, Christian, Lichtenauer, Michael, Hoppe, Uta C., Kaufmann, Reinhard, Osmani, Venet, Wernly, Bernhard
Format: Article
Language:English
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Summary:Summary Severe hyperlactatemia (>10mmol/L) or impaired lactate metabolism are known to correlate with increased mortality. The maximum lactate concentration on day 1 of 10,724 septic patients from the eICU Collaborative Research Database was analyzed and patients were divided into three groups based on maximum lactate in the first 24 h (
ISSN:0043-5325
1613-7671
DOI:10.1007/s00508-022-02130-y