Cardiometabolic indices predict hypogonadism in male patients with type 2 diabetes

Purpose To evaluate in men with type 2 diabetes the association of cardiometabolic indices [Visceral Adiposity Index (VAI), Triglyceride Glucose Index (TyG), and lipid accumulation product (LAP)] with total testosterone (TT) levels, and their predictive cut-off values in identifying hypogonadism. Me...

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Bibliographic Details
Published in:Journal of endocrinological investigation 2023-03, Vol.46 (3), p.599-608
Main Authors: Caretta, N., Facondo, P., Mereu, S., Delbarba, A., Crepaldi, M. C., Vedovato, M., Avogaro, A., Ferlin, A.
Format: Article
Language:English
Subjects:
Adipose tissue
Adiposity
Body Mass Index
Cardiovascular Diseases - complications
Diabetes
Diabetes mellitus (non-insulin dependent)
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - epidemiology
Endocrinology
Glucose
Humans
Hypogonadism
Hypogonadism - diagnosis
Hypogonadism - epidemiology
Hypogonadism - etiology
Internal Medicine
Male
Medicine
Medicine & Public Health
Metabolic Diseases
Obesity, Abdominal - complications
Original
Original Article
Testosterone
Triglycerides - metabolism
Waist Circumference
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Summary:Purpose To evaluate in men with type 2 diabetes the association of cardiometabolic indices [Visceral Adiposity Index (VAI), Triglyceride Glucose Index (TyG), and lipid accumulation product (LAP)] with total testosterone (TT) levels, and their predictive cut-off values in identifying hypogonadism. Methods 265 consecutive men aged 40–70 years with type 2 diabetes performed an andrological evaluation; metabolic parameters and TT were determined. Receiver operating characteristic (ROC) curves were used to identify cut-off values of cardiometabolic indices in predicting low testosterone (TT 
ISSN:1720-8386
0391-4097
1720-8386
DOI:10.1007/s40618-022-01941-0