Doppler Echocardiography Combined with NTproBNP/BNP in the Diagnosis of Pulmonary Artery Hypertension Associated with Congenital Heart Disease

• Published in: Computational and mathematical methods in medicine 2023, Vol.2023 (1), p.1896026-1896026
• Main Authors: Zhang, Xi, Zhai, Zhinan, Geng, Xu, Zhu, Yanbo, Yang, Shijuan, Chen, Tongyun, Wu, Xue, Zhang, Jingkun, Guo, Zhi-Gang, Hou, Min
• Format: Article
• Language: English
• Subjects: Echocardiography, Doppler - methods; Heart Defects, Congenital - complications; Humans; Hypertension, Pulmonary; Pulmonary Arterial Hypertension; Pulmonary Artery - diagnostic imaging; Retrospective Studies
• ISSN: 1748-670X; 1748-6718
• DOI: 10.1155/2023/1896026

Background. Pulmonary artery hypertension (PAH) is a common complication of congenital heart disease (CHD) and is associated with worse outcomes and increased mortality. The Doppler echocardiography (DE) is a commonly used imaging tool for both diagnosis and follow-up examination of PAH. Here is to evaluate the diagnostic performance of DE combined with NTproBNP/BNP as screening strategy in PAH patients with CHD. Methods. A retrospective study in 64 patients with CHD has been carried out to compare estimate pulmonary artery systolic pressure (PASP) measured with DE to that measured with right heart catheterization (RHC). The Pearson correlation analyses were used to calculate the correlation coefficients between RHC and DE. The Bland-Altman analyses were carried out to assess the agreement between the two methods. ROC analyses were used to evaluate the diagnostic performance of DE, NTproBNP/BNP, and DE combined with NTproBNP/BNP. Results. Our data have demonstrated that a mild correlation (r=0.4401, P