Selenium-Based Fluorescence Probes for the Detection of Bioactive Molecules

Chemistry of organoselenium reagents have now become an important tool of synthetic organic and medicinal chemistry. These reagents activate the olefinic double bonds and used to archive the number of organic transformations under mild reaction conditions. A number of organoselenium compounds have b...

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Bibliographic Details
Published in:ACS Organic & Inorganic Au 2022-08, Vol.2 (4), p.262-288
Main Authors: Mamgain, Ritu, Singh, Fateh V.
Format: Article
Language:English
Subjects:
Review
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Summary:Chemistry of organoselenium reagents have now become an important tool of synthetic organic and medicinal chemistry. These reagents activate the olefinic double bonds and used to archive the number of organic transformations under mild reaction conditions. A number of organoselenium compounds have been identified as potent oxidants. Recently, various organoselenium species have been employed as chemical sensors for detecting toxic metals. Moreover, a number of selenium-based fluorescent probes have been developed for detecting harmful peroxides and ROS. In this review article, the synthesis of selenium-based fluorescent probes will be covered including their application in the detection of toxic metals and harmful peroxides including ROS.
ISSN:2694-247X
2694-247X
DOI:10.1021/acsorginorgau.1c00047