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A DR/NIR Hybrid Polymeric Tool for Functional Bio-Coatings: Theoretical Study, Cytotoxicity, and Antimicrobial Activity
Among modern biomaterials, hybrid tools containing an organic component and a metal cation are recognized as added value, and, for many advanced biomedical applications, synthetic polymers are used as thin protective/functional coatings for medical or prosthetic devices and implants. These materials...
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| Published in: | Polymers 2023-02, Vol.15 (4), p.883 |
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| Main Authors: | , , , , , , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c482t-47126447b7f8eabc7c0d7cb9820933420f58d509d924d1cc15bca57b17ba367a3 |
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| cites | cdi_FETCH-LOGICAL-c482t-47126447b7f8eabc7c0d7cb9820933420f58d509d924d1cc15bca57b17ba367a3 |
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| container_issue | 4 |
| container_start_page | 883 |
| container_title | Polymers |
| container_volume | 15 |
| creator | Diana, Rosita Gentile, Francesco Silvio Concilio, Simona Petrella, Antonello Belvedere, Raffaella Schibeci, Martina Arciello, Angela Di Costanzo, Luigi Panunzi, Barbara |
| description | Among modern biomaterials, hybrid tools containing an organic component and a metal cation are recognized as added value, and, for many advanced biomedical applications, synthetic polymers are used as thin protective/functional coatings for medical or prosthetic devices and implants. These materials require specific non-degradability, biocompatibility, antimicrobial, and antiproliferative properties to address safety aspects concerning their use in medicine. Moreover, bioimaging monitoring of the biomedical device and/or implant through biological tissues is a desirable ability. This article reports a novel hybrid metallopolymer obtained by grafting zinc-coordinated fragments to an organic polymeric matrix. This hybrid polymer, owing to its relevant emission in the deep red to near-infrared (DR/NIR) region, is monitorable; therefore, it represents a potential material for biomedical coating. Furthermore, it shows good biocompatibility and adhesion properties and excellent stability in slightly acidic/basic water solutions. Finally, in contact with the superficial layers of human skin, it shows antimicrobial properties against
bacterial strains. |
| doi_str_mv | 10.3390/polym15040883 |
| format | article |
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| ispartof | Polymers, 2023-02, Vol.15 (4), p.883 |
| issn | 2073-4360 2073-4360 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9967255 |
| source | Publicly Available Content (ProQuest); PubMed Central |
| subjects | Antiinfectives and antibacterials Antimicrobial agents Bioassays Biocompatibility Biological products Biomedical engineering Biomedical materials Biopolymers Coatings Ethanol Implants, Artificial Medical imaging Methicillin Near infrared radiation Phase transitions Polymers Printed materials Prostheses Prosthesis Protective coatings Surgical implants Tissues Toxicity Transplants & implants Zinc |
| title | A DR/NIR Hybrid Polymeric Tool for Functional Bio-Coatings: Theoretical Study, Cytotoxicity, and Antimicrobial Activity |
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