Focal liver lesions other than hepatocellular carcinoma in cirrhosis: Diagnostic challenges

Liver cirrhosis is associated with regenerative nodules and an increased risk of developing hepatocellular carcinoma (HCC). However, other benign and malignant liver lesions may also occur. Differentiating the other lesions from HCC is important for further therapeutic decisions. This review discuss...

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Bibliographic Details
Published in:Journal of translational internal medicine 2023-01, Vol.10 (4), p.308-327
Main Authors: Möller, Kathleen, Safai Zadeh, Ehsan, Görg, Christian, Dong, Yi, Cui, Xinwu, Lim, Adrian, Molo, Chiara de, Serra, Carla, Martín Algíbez, Ana, Berzigotti, Analisa, Piscaglia, Fabio, Faiss, Siegbert, Dietrich, Christoph F.
Format: Article
Language:English
Subjects:
cirrhosis
contrast-enhanced ultrasonography
focal liver lesions
hepatocellular carcinoma
Review
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Summary:Liver cirrhosis is associated with regenerative nodules and an increased risk of developing hepatocellular carcinoma (HCC). However, other benign and malignant liver lesions may also occur. Differentiating the other lesions from HCC is important for further therapeutic decisions. This review discusses the characteristics of non-HCC liver lesions in cirrhosis and their consequent appearance on contrast-enhanced ultrasonography (CEUS) with consideration of other imaging. Knowledge of this data would be helpful in avoiding misdiagnoses.
ISSN:2224-4018
2450-131X
2224-4018
DOI:10.2478/jtim-2022-0068