Recurrent Brain Metastasis Versus Radiation-Induced Necrosis: A Case Report and Literature Review

Radiotherapy is the cornerstone of brain metastasis management. With the advancement of therapies, patients are living longer, exposing them to the long-term effects of radiotherapy. Using concurrent or sequential chemotherapy, targeted agents, and immune checkpoint inhibitors may increase the incid...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2023-01, Vol.15 (1), p.e34400
Main Authors: Sweidan, Hisham, Jarrah, Abdullah, Zhu, Feng, AlQasem, Sarah, Manasrah, Nouraldeen, Chaudhary, Ahmed Jamal
Format: Article
Language:English
Subjects:
Abscesses
Brain cancer
Case reports
Chemotherapy
Drug dosages
Edema
Hospitals
Internal Medicine
Lung cancer
Medicine
Metastasis
Necrosis
Oncology
Pathology
Patients
Radiation Oncology
Radiation therapy
Steroids
Surgery
Tumors
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Summary:Radiotherapy is the cornerstone of brain metastasis management. With the advancement of therapies, patients are living longer, exposing them to the long-term effects of radiotherapy. Using concurrent or sequential chemotherapy, targeted agents, and immune checkpoint inhibitors may increase the incidence and severity of radiation-induced toxicity. Recurrent metastasis and radiation necrosis (RN) appear indistinguishable on neuroimaging, making it a diagnostic dilemma for clinicians. Here, we present a case of RN in a 65-year-old male patient who previously had brain metastasis (BM) from primary lung cancer, misdiagnosed initially as recurrent BM.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.34400