Pseudoclitoromegaly from acute T-cell lymphoblastic leukemia

A 7-year-old girl presented with painful genital enlargement, which was first believed to be clitoromegaly of hormonal origin. However, on the physical exam the clitoris was not visible and the prepuce and labia minora were enlarged and tender. Magnetic resonance imaging demonstrated an infiltrative...

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Bibliographic Details
Published in:Proceedings - Baylor University. Medical Center 2023, Vol.36 (2), p.237-239
Main Authors: Birkemeier, Krista, Wills, Hale E, Issa, Tesneem, Farris, Amanda, Stacey, Joanna, Greene, Pamela, Dawood, Wajahat, Desai, Kurren, Laborde, Carrie, Trotter, Bradley
Format: Article
Language:English
Subjects:
Case Report
Case reports
Case Studies
Leukemia
Urogenital system
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Summary:A 7-year-old girl presented with painful genital enlargement, which was first believed to be clitoromegaly of hormonal origin. However, on the physical exam the clitoris was not visible and the prepuce and labia minora were enlarged and tender. Magnetic resonance imaging demonstrated an infiltrative abnormal signal with restricted diffusion involving the enlarged clitoris and adjacent soft tissues of the prepuce and labia minora, confirming a nonhormonal infiltrative malignancy. The same abnormal signal was present in enlarged inguinal lymph nodes, the kidneys, and an anterior mediastinal mass. The pathologic diagnosis was T-cell acute lymphoblastic leukemia.
ISSN:0899-8280
1525-3252
DOI:10.1080/08998280.2022.2139508