Brief Report: Diabetic Keto-Acidosis (DKA) Induced Hypothermia May Be Neuroprotective in Cardiac Arrest

Despite the decreased survival associated with diabetes with out-of-hospital cardiac arrest and the overall low survival to hospital discharge, we would like to present two cases of OHCA in diabetics who despite prolonged resuscitation efforts had complete neurological recovery likely due to concomi...

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Bibliographic Details
Published in:Journal of critical care medicine (Universitatea de Medicină și Farmacie din Târgu-Mureș) 2023-02, Vol.9 (1), p.39-42
Main Authors: Shiber, Joseph, Fontane, Emily
Format: Article
Language:English
Subjects:
Acidosis
Cardiac arrest
Cardiopulmonary resuscitation
Case Report
CPR
Diabetes
Diabetic ketoacidosis
Extubation
Glucose
Heat
Hypothermia
Insulin
Mortality
neuroprotection
Patients
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Summary:Despite the decreased survival associated with diabetes with out-of-hospital cardiac arrest and the overall low survival to hospital discharge, we would like to present two cases of OHCA in diabetics who despite prolonged resuscitation efforts had complete neurological recovery likely due to concomitant hypothermia. There is a steady decreasing rate of ROSC with longer durations of CPR so that outcomes are best when 30-40 minutes). It has been previously recognized that hypothermia prior to cardiac arrest can be neurologically protective even with up to 9 hours of cardiopulmonary resuscitation. Hypothermia has been associated with DKA and although often indicates sepsis with mortality rates of 30-60%, it may indeed be protective if occurring prior to cardiac arrest. The critical factor for neuroprotection may be a slow drop to a temperature
ISSN:2393-1817
2393-1809
2393-1817
DOI:10.2478/jccm-2023-0004