Vascular function in women: when studying perimenopause is peri important

[...]we wish to highlight the importance of considering (i) the menopausal transition as a period of accelerated risk and clinical versus statistical significance, (ii) subject characteristics that may alter vascular ageing trajectories, and (iii) the paucity of data on cerebrovascular haemodynamics...

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Bibliographic Details
Published in:Experimental physiology 2023-03, Vol.108 (3), p.333-335
Main Authors: DuBose, Lyndsey E., Lefferts, Wesley K.
Format: Article
Language:English
Subjects:
Aging
Alzheimer's disease
Authorship
brain
Brain research
Clinical significance
Cross-sectional studies
Disease
Estradiol
Exercise
Female
Health risk assessment
Hemodynamics
Hormones
Humans
Menopause
Menstruation
oestradiol
Perimenopause
Physical activity
Physical fitness
Physiology
vascular function
Veins & arteries
Womens health
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Description
Summary:[...]we wish to highlight the importance of considering (i) the menopausal transition as a period of accelerated risk and clinical versus statistical significance, (ii) subject characteristics that may alter vascular ageing trajectories, and (iii) the paucity of data on cerebrovascular haemodynamics during menopause and importance of considering differing vascular methodology. [...]the limited literature examining cerebrovascular haemodynamics with menopause is inconsistent. [...]studies should comprehensively assess and report participant characteristics (i.e., physical activity, social determinants of health, menopause stage and symptoms) that may interact to alter vascular ageing trajectories across the menopausal transition and increase scientific reproducibility.
ISSN:0958-0670
1469-445X
DOI:10.1113/EP091066