Secretome of umbilical cord mesenchymal stem cells: Potential effects on melanoma

Melanoma, a tumor resulting from the malignant transformation of melanocytes, is characterized by its aggressive nature and propensity to metastasize. Current treatment options for advanced melanoma are limited and mostly ineffective, highlighting the need for novel therapeutic approaches. Mesenchym...

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Bibliographic Details
Published in:Stem cells translational medicine 2023-09, Vol.12, Issue Supplement_1
Main Authors: Fernandes, Pablo , Gomes, Andreia , Coelho, Pedro
Format: Article
Language:English
Subjects:
Human umbilical cord
Melanoma
Online Access:Get full text
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Summary:Melanoma, a tumor resulting from the malignant transformation of melanocytes, is characterized by its aggressive nature and propensity to metastasize. Current treatment options for advanced melanoma are limited and mostly ineffective, highlighting the need for novel therapeutic approaches. Mesenchymal stem cells (MSCs) have increased considerable attention due to their anti-cancer and immunomodulatory properties. In particular, human umbilical cord MSCs (hUCMSCs) have shown promise in various therapeutic applications.
ISSN:2157-6580
DOI:10.1093/stcltm/szad047.028