Penems and Related Substances

The discovery of the penicillins, as exemplified by penicillin G (1) - one of the earliest known members of the class - and of the cephalosporins, of which the first to be isolated was cephalosporin C (2), laid the basis for one of the most spectacular chapters in the history of medicine.

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Bibliographic Details
Published in:Philosophical transactions of the Royal Society of London. Series B, Biological sciences Biological sciences, 1980-05, Vol.289 (1036), p.239-250
Main Author: Woodward, R. B.
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents - history
Anti-Bacterial Agents - pharmacology
Antibacterials
Antibiotics
Bacteria - drug effects
Carbapenems
Cephalosporins
Cephalosporins - chemical synthesis
Chemistry
Crystal structure
Enantiomers
Esters
History of medicine
History, 20th Century
Molecular Conformation
Penicillin
Penicillins - history
Reactivity
Staphylococcus aureus
Stereoisomerism
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Description
Summary:The discovery of the penicillins, as exemplified by penicillin G (1) - one of the earliest known members of the class - and of the cephalosporins, of which the first to be isolated was cephalosporin C (2), laid the basis for one of the most spectacular chapters in the history of medicine.
ISSN:0080-4622
0962-8436
2054-0280
DOI:10.1098/rstb.1980.0042