"Clickable" polymer nanoparticles: a modular scaffold for surface functionalizationElectronic supplementary information (ESI) available: Detailed experimental procedures, materials, instrumentation, and characterization. See DOI: 10.1039/c0cc00232a

The versatility of copper-catalyzed alkyne-azide coupling (CuAAC) in functionalizing drug-loaded polymer nanoparticles is demonstrated via the modification of surfaces of acetylene-functionalized PNPs with folate, biotin, and gold nanoparticles. "Click" chemistry is used to functionalize d...

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Bibliographic Details
Main Authors: Krovi, Sai Archana, Smith, DeeDee, Nguyen, SonBinh T
Format: Article
Language:English
Online Access:Get full text
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Summary:The versatility of copper-catalyzed alkyne-azide coupling (CuAAC) in functionalizing drug-loaded polymer nanoparticles is demonstrated via the modification of surfaces of acetylene-functionalized PNPs with folate, biotin, and gold nanoparticles. "Click" chemistry is used to functionalize drug-loaded, acetylene-functionalized polymer nanoparticles (PNPs) with folate, biotin, and gold nanoparticles.
ISSN:1359-7345
1364-548X
DOI:10.1039/c0cc00232a