Dehydrogenative Heck coupling of biologically relevant N-heteroarenes with alkenes: discovery of fluorescent core frameworksElectronic supplementary information (ESI) available: Detailed experimental procedures and analytical data. See DOI: 10.1039/c2cc17557f

A Pd/Cu-catalyzed dehydrogenative Heck coupling is established that allows direct alkenylation of various biologically relevant N-heteroarenes with alkenes. The resulting -extended alkenylated N-heteroarenes exhibit interesting fluorescent properties and have proven to be potentially useful fluoresc...

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Main Authors: Huang, Yumin, Song, Feijie, Wang, Zhen, Xi, Peihua, Wu, Ningjie, Wang, Zhigang, Lan, Jingbo, You, Jingsong
Format: Article
Language:English
Online Access:Get full text
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Summary:A Pd/Cu-catalyzed dehydrogenative Heck coupling is established that allows direct alkenylation of various biologically relevant N-heteroarenes with alkenes. The resulting -extended alkenylated N-heteroarenes exhibit interesting fluorescent properties and have proven to be potentially useful fluorescent probes for bioimaging. A dehydrogenative Heck coupling allows direct alkenylation of various biologically relevant N-heteroarenes with alkenes to give alkenylated N-heteroarenes that have proven to be potentially useful fluorescent probes for bioimaging.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc17557f