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"One-pot" fabrication of clickable monoliths for enzyme reactorsElectronic supplementary information (ESI) available: Experimental details, comparison of the alkynyl-silica monolith and the IP-silica monolith, comparison of modified HRP activity, evaluation of the HRP-reactor made from the alkynyl-silica monolith. See DOI: 10.1039/c2cc37974k

A simple, novel "one-pot" approach was developed for the preparation of organic-silica hybrid monoliths. Two clickable monoliths functionalized with either azido or alkynyl moieties were prepared. The clickable monoliths were further used for the fabrication of enzyme reactors via "cl...

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Bibliographic Details
Main Authors: Wu, Minghuo, Zhang, Hongquan, Wang, Zhixin, Shen, Shengwen, Le, X. Chris, Li, Xing-Fang
Format: Article
Language:English
Online Access:Get full text
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Summary:A simple, novel "one-pot" approach was developed for the preparation of organic-silica hybrid monoliths. Two clickable monoliths functionalized with either azido or alkynyl moieties were prepared. The clickable monoliths were further used for the fabrication of enzyme reactors via "click chemistry". We report one-pot synthesis of clickable capillary monoliths and their applications to produce enzyme microreactors.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc37974k