Voltage controlled nano-injection system for single-cell surgeryElectronic supplementary information (ESI) available. See DOI: 10.1039/c2nr31700a

Manipulation and analysis of single cells is the next frontier in understanding processes that control the function and fate of cells. Herein we describe a single-cell injection platform based on nanopipettes. The system uses scanning microscopy techniques to detect cell surfaces, and voltage pulses...

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Main Authors: Adam Seger, R, Actis, Paolo, Penfold, Catherine, Maalouf, Michelle, Vilozny, Boaz, Pourmand, Nader
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Actis, Paolo
Penfold, Catherine
Maalouf, Michelle
Vilozny, Boaz
Pourmand, Nader
description Manipulation and analysis of single cells is the next frontier in understanding processes that control the function and fate of cells. Herein we describe a single-cell injection platform based on nanopipettes. The system uses scanning microscopy techniques to detect cell surfaces, and voltage pulses to deliver molecules into individual cells. As a proof of concept, we injected adherent mammalian cells with fluorescent dyes. We developed a system that uses scanning microscopy techniques to detect cell surfaces, and voltage pulses to deliver molecules into individual cells.
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title Voltage controlled nano-injection system for single-cell surgeryElectronic supplementary information (ESI) available. See DOI: 10.1039/c2nr31700a
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