Stereoselective synthesis of cyclic amino acids via asymmetric phase-transfer catalytic alkylationElectronic supplementary information (ESI) available: Experimental details. See DOI: 10.1039/c2ob26778k

An asymmetric synthesis of cyclic amino acids having piperidine and azepane core structures was realized starting from readily available glycine and alanine esters by combination of phase-transfer catalyzed asymmetric alkylation and subsequent reductive amination. An asymmetric synthesis of cyclic a...

Full description

Saved in:
Bibliographic Details
Main Authors: Kano, Taichi, Kumano, Takeshi, Sakamoto, Ryu, Maruoka, Keiji
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:An asymmetric synthesis of cyclic amino acids having piperidine and azepane core structures was realized starting from readily available glycine and alanine esters by combination of phase-transfer catalyzed asymmetric alkylation and subsequent reductive amination. An asymmetric synthesis of cyclic amino acids was realized by combination of phase-transfer catalyzed asymmetric alkylation and subsequent reductive amination.
ISSN:1477-0520
1477-0539
DOI:10.1039/c2ob26778k