A synthesis of -amino acids via direct reductive carboxylation of imines with carbon dioxideElectronic supplementary information (ESI) available: Full experimental procedures, characterization data, NMR spectra. See DOI: 10.1039/c3cc42057d

A method for the synthesis of -amino acids by direct reductive carboxylation of aromatic imines with CO 2 is described. The protocol employs readily available commercial reagents and serves as a one-step alternative to the Strecker synthesis. A synthesis of -amino acids by direct reductive carboxyla...

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Bibliographic Details
Main Authors: Sathe, Ajay A, Hartline, Douglas R, Radosevich, Alexander T
Format: Article
Language:English
Online Access:Get full text
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Summary:A method for the synthesis of -amino acids by direct reductive carboxylation of aromatic imines with CO 2 is described. The protocol employs readily available commercial reagents and serves as a one-step alternative to the Strecker synthesis. A synthesis of -amino acids by direct reductive carboxylation of aromatic imines with CO 2 using readily available reagents is described.
ISSN:1359-7345
1364-548X
DOI:10.1039/c3cc42057d