Pyrene-imidazolium complexed graphene for the selective fluorescent detection of G-quadruplex forming DNAElectronic supplementary information (ESI) available: Detailed experimental and synthesis procedures as well as sequence details and XPS. See DOI: 10.1039/c3cc46744a

A unique system has been developed for quantifying G-quadruplex forming DNA down to picomolar levels for future applications in telomeric assessment. Pyrene-imidazolium captured in high amounts on the surface of reduced graphene oxide shells allows specific DNA sequence detection by complex formatio...

Full description

Saved in:
Bibliographic Details
Main Authors: Moon, Seung Jin, Park, So Hyeon, Jaworski, Justyn, Jung, Jong Hwa
Format: Article
Language:English
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A unique system has been developed for quantifying G-quadruplex forming DNA down to picomolar levels for future applications in telomeric assessment. Pyrene-imidazolium captured in high amounts on the surface of reduced graphene oxide shells allows specific DNA sequence detection by complex formation resulting in release and fluorescence enhancement of pyrene-imidazolium. Selective complex formation with G-quadruplex forming DNA provides quantifiable fluorescence enhancement of pyrene-imidazolium ( PI ) upon release from the surface of reduced graphene oxide shells even at picomolar amounts.
ISSN:1359-7345
1364-548X
DOI:10.1039/c3cc46744a