Pyrene-imidazolium complexed graphene for the selective fluorescent detection of G-quadruplex forming DNAElectronic supplementary information (ESI) available: Detailed experimental and synthesis procedures as well as sequence details and XPS. See DOI: 10.1039/c3cc46744a

A unique system has been developed for quantifying G-quadruplex forming DNA down to picomolar levels for future applications in telomeric assessment. Pyrene-imidazolium captured in high amounts on the surface of reduced graphene oxide shells allows specific DNA sequence detection by complex formatio...

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Main Authors: Moon, Seung Jin, Park, So Hyeon, Jaworski, Justyn, Jung, Jong Hwa
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creator Moon, Seung Jin
Park, So Hyeon
Jaworski, Justyn
Jung, Jong Hwa
description A unique system has been developed for quantifying G-quadruplex forming DNA down to picomolar levels for future applications in telomeric assessment. Pyrene-imidazolium captured in high amounts on the surface of reduced graphene oxide shells allows specific DNA sequence detection by complex formation resulting in release and fluorescence enhancement of pyrene-imidazolium. Selective complex formation with G-quadruplex forming DNA provides quantifiable fluorescence enhancement of pyrene-imidazolium ( PI ) upon release from the surface of reduced graphene oxide shells even at picomolar amounts.
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title Pyrene-imidazolium complexed graphene for the selective fluorescent detection of G-quadruplex forming DNAElectronic supplementary information (ESI) available: Detailed experimental and synthesis procedures as well as sequence details and XPS. See DOI: 10.1039/c3cc46744a
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