FITC-quencher based caspase 3-activatable nanoprobes for effectively sensing caspase 3 in vitro and in cellsElectronic supplementary information (ESI) available. See DOI: 10.1039/c3nr03339b

By employing fluorescence resonance energy transfer (FRET) quenching, we rationally designed two new FITC-quencher based nanoprobes for effectively sensing caspase 3 (Casp3) in vitro and in cells. Our nanoprobes hold promise for assessing the chemotherapeutic effect of cancer treatment. FRET-quenchi...

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Main Authors: Tang, Anming, Mei, Bin, Wang, Weijuan, Hu, Wanglai, Li, Fang, Zhou, Jun, Yang, Qing, Cui, Hua, Wu, Mian, Liang, Gaolin
Format: Article
Language:English
Online Access:Get full text
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Summary:By employing fluorescence resonance energy transfer (FRET) quenching, we rationally designed two new FITC-quencher based nanoprobes for effectively sensing caspase 3 (Casp3) in vitro and in cells. Our nanoprobes hold promise for assessing the chemotherapeutic effect of cancer treatment. FRET-quenching based caspase 3-activatable new nanoprobes were developed for effectively sensing caspase 3 activity in vitro and in apoptotic cells.
ISSN:2040-3364
2040-3372
DOI:10.1039/c3nr03339b