No photocatalyst required - versatile, visible light mediated transformations with polyhalomethanesElectronic supplementary information (ESI) available: Full experimental details and characterization. CCDC 993641. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4cc10270c

A visible light mediated, but photocatalyst-free method for the oxidative α-CH functionalization of tertiary amines with a broad scope of carbon- and heteroatom nucleophiles using polyhalomethanes has been developed. In addition, the pivotal visible light triggered activation of polyhalomethanes off...

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Main Authors: Franz, Johannes F, Kraus, Wolfgang B, Zeitler, Kirsten
Format: Article
Language:English
Online Access:Get full text
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Summary:A visible light mediated, but photocatalyst-free method for the oxidative α-CH functionalization of tertiary amines with a broad scope of carbon- and heteroatom nucleophiles using polyhalomethanes has been developed. In addition, the pivotal visible light triggered activation of polyhalomethanes offers mild conditions for efficient Kharasch-type additions onto non-activated olefins. Preliminary mechanistic studies are reported. Visible light activation of polyhalomethanes offers a versatile, photocatalyst-free method for the α-CH functionalization of amines and for regioselective Kharasch-type additions.
ISSN:1359-7345
1364-548X
DOI:10.1039/c4cc10270c